2-Amino-5-bromo-3-hydroxypyridine - CAS 39903-01-0
Catalog: |
BB024195 |
Product Name: |
2-Amino-5-bromo-3-hydroxypyridine |
CAS: |
39903-01-0 |
Synonyms: |
2-amino-5-bromo-3-pyridinol; 2-amino-5-bromopyridin-3-ol |
IUPAC Name: | 2-amino-5-bromopyridin-3-ol |
Description: | 2-Amino-5-bromo-3-hydroxypyridine (CAS# 39903-01-0) is a useful intermediate for organic synthesis. It is used in the synthesis of Ethyl 6-bromo-8-hydroxyimidazo[1,2-a]pyridine-3-carboxylate derivatives with anti-hepatitis B virus (HBV) activity. |
Molecular Weight: | 189.01 |
Molecular Formula: | C5H5BrN2O |
Canonical SMILES: | C1=C(C(=NC=C1Br)N)O |
InChI: | InChI=1S/C5H5BrN2O/c6-3-1-4(9)5(7)8-2-3/h1-2,9H,(H2,7,8) |
InChI Key: | YQADLKDQAXAIKW-UHFFFAOYSA-N |
Boiling Point: | 295.13 °C at 760 mmHg |
Density: | 1.826 g/cm3 |
MDL: | MFCD09744143 |
LogP: | 1.71310 |
GHS Hazard Statement: | H302 (23.08%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P261, P264, P270, P271, P272, P280, P301+P312, P302+P352, P304+P312, P304+P340, P312, P321, P322, P330, P333+P313, P363, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
CN-111943885-A | Synthetic method of Laolatinib intermediate 2-amino-5-bromo-3-hydroxypyridine | 20200701 |
WO-2021013742-A1 | 5,8-disubstituted-[1,2,4]triazolo[1,5-a]pyridinyl and 5,8-disubstituted-imidazo[1,2-a]pyridine derivatives useful as inhibitors of enteropeptidase | 20190719 |
WO-2020263980-A1 | Imidazo[1,2-a]pyridinyl derivatives and their use in the treatment of disease | 20190627 |
CN-109942485-A | A kind of gram of azoles replaces the synthetic method of Buddhist nun's intermediate | 20190411 |
WO-2020150626-A1 | Imidazo[1,2-a]pyridinyl derivatives as irak4 inhibitors | 20190118 |
PMID | Publication Date | Title | Journal |
21522402 | 20110219 | 5-Bromo-3-(indan-1-yl-oxy)pyridin-2-amine | Acta crystallographica. Section E, Structure reports online |
Complexity: | 101 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 187.95853 |
Formal Charge: | 0 |
Heavy Atom Count: | 9 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 187.95853 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 59.1 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 0.8 |
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