2-Amino-5-(4-fluorophenyl)-1,3,4-thiadiazole - CAS 942-70-1

Name: 2-Amino-5-(4-fluorophenyl)-1,3,4-thiadiazole
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog:	BB041258
Product Name:	2-Amino-5-(4-fluorophenyl)-1,3,4-thiadiazole
CAS:	942-70-1
Synonyms:	5-(4-fluorophenyl)-1,3,4-thiadiazol-2-amine

Technical Data

Safety and Hazards

Patents

Literatures

Computed Properties

IUPAC Name:	5-(4-fluorophenyl)-1,3,4-thiadiazol-2-amine
Description:	2-Amino-5-(4-fluorophenyl)-1,3,4-thiadiazole (CAS# 942-70-1) is a useful research chemical.
Molecular Weight:	195.22
Molecular Formula:	C8H6FN3S
Canonical SMILES:	C1=CC(=CC=C1C2=NN=C(S2)N)F
InChI:	InChI=1S/C8H6FN3S/c9-6-3-1-5(2-4-6)7-11-12-8(10)13-7/h1-4H,(H2,10,12)
InChI Key:	WRSVCKNLHZWSNJ-UHFFFAOYSA-N
Boiling Point:	351.9 °C at 760 mmHg
Melting Point:	238-243 °C
Purity:	95 %
Density:	1.423 g/cm³
Appearance:	White to tan powder or crystals
MDL:	MFCD00981219
LogP:	2.50760

Related Products

Online Inquiry

Name:

* Phone:

* Service & Products of Interested:

Project Description:

* Quantity:

* Email:

* Verification Code:

Customer Support

If the product you need is not in our catalog, please contact us in time to submit your needs. You can help our website get better and better. Why not submit the request today?

Submit Requirement

Customer Centered

Global Delivery

Warehouses in multiple cities to ensure fast delivery

Quality Assurance

Strict process parameter control to ensure product quality

Large Stock

> 20,000 building blocks and intermediates from stock

Process Scale-up

Process scale-up from lab to industrial scale

Flexible Batch Size

Flexible batch size for diverse industrial demands

Related Functional Groups

Fluorinated Building Blocks

[1006473-17-1]C13H15F2N3
[(2,3-Difluorophenyl)methyl][(1,3-dimethylpyrazol-4-yl)methyl]amine
[479552-94-8]C8H5F3N2O3S
1H-Pyrrolo[2,3-b]pyridin-4-yl trifluoromethanesulfonate
[1018125-51-3]C12H12F3N3O2
2-(6-Ethyl-3-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid
[1170836-29-9]C12H12F3N5
3-(1',3'-Dimethyl-5-(trifluoromethyl)-1'H,2H-[3,4'-bipyrazol]-2-yl)propanenitrile
[459836-92-1]C8H6F2O2
3,6-Difluoro-2-methylbenzoic acid
[1211518-11-4]C4H2ClF3N4
4-chloro-6-(trifluoromethyl)-1,3,5-triazin-2-amine

Other Pyrimidines

[479552-94-8]C8H5F3N2O3S
1H-Pyrrolo[2,3-b]pyridin-4-yl trifluoromethanesulfonate
[452-76-6]C7H6F2
2,4-Difluorotoluene
[351-28-0]C8H8FNO
3'-Fluoroacetanilide
[832739-73-8]C10H6Cl2N2S
4-(3,5-Dichlorophenyl)pyrimidine-2-thiol
[81290-20-2]C4H9F3Si
Trimethyl(trifluoromethyl)silane
[1489-53-8]C6H3F3
1,2,3-Trifluorobenzene

Oxadiazole/Thiadiazole

[1018125-37-5]C11H9FN2O3
Ethyl 3-(2-fluorophenyl)-1,2,4-oxadiazole-5-carboxylate
[73185-75-8]C11H9N3O5
Ethyl 3-(3-nitrophenyl)-1,2,4-oxadiazole-5-carboxylate
[478030-57-8]C12H9F3N2O3
Ethyl 3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole-5-carboxylate
[880361-90-0]C10H11N3O
Methyl-(5-phenyl-[1,3,4]oxadiazol-2-ylmethyl)-amine
[938007-34-2]C12H12N4O4
N-(2-Aminoethyl)-3-(1,3-benzodioxol-5-yl)-1,2,4-oxadiazole-5-carboxamide
[938007-35-3]C13H16N4O4
N-(2-Aminoethyl)-3-(3,4-dimethoxyphenyl)-1,2,4-oxadiazole-5-carboxamide

GHS Hazard Statement:	H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
Precautionary Statement:	P264, P270, P280, P301+P312, P305+P351+P338, P330, P337+P313, and P501
Signal Word:	Warning

Publication Number	Title	Priority Date
WO-2020116972-A1	Compounds having pde9a inhibitory activity, and pharmaceutical uses thereof	20181206
KR-20200068996-A	Compound for inhibiting PDE9A and medical uses thereof	20181206
CN-113166159-A	Compound with PDE9A inhibitory activity and pharmaceutical use thereof	20181206
EP-3892622-A1	Compounds having pde9a inhibitory activity, and pharmaceutical uses thereof	20181206
CN-107001351-B	Derivatives of 2- (1,2, 4-triazol-3-ylsulfanyl) -N-1,3, 4-thiadiazol-2-ylacetamide useful in the treatment of, in particular, diabetes	20141029

PMID	Publication Date	Title	Journal
24161679	20131101	2-Heteroarylimino-5-arylidene-4-thiazolidinones as a new class of non-nucleoside inhibitors of HCV NS5B polymerase	European journal of medicinal chemistry
21583266	20090529	5-(3-Fluoro-phen-yl)-1,3,4-thia-diazol-2-amine	Acta crystallographica. Section E, Structure reports online

Complexity:	173
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	195.02664654
Formal Charge:	0
Heavy Atom Count:	13
Hydrogen Bond Acceptor Count:	5
Hydrogen Bond Donor Count:	1
Isotope Atom Count:	0
Monoisotopic Mass:	195.02664654
Rotatable Bond Count:	1
Topological Polar Surface Area:	80 Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	1.8