2-Amino-3-pyridinecarbonitrile - CAS 24517-64-4
Catalog: |
BB018512 |
Product Name: |
2-Amino-3-pyridinecarbonitrile |
CAS: |
24517-64-4 |
Synonyms: |
2-aminopyridine-3-carbonitrile |
IUPAC Name: | 2-aminopyridine-3-carbonitrile |
Description: | 2-Amino-3-pyridinecarbonitrile (CAS# 24517-64-4) is used as a reagent in the synthesis of novel imidazo[1,2-a]pyridine derivatives as potent c-Met inhibitors and antimycobacterials. |
Molecular Weight: | 119.12 |
Molecular Formula: | C6H5N3 |
Canonical SMILES: | C1=CC(=C(N=C1)N)C#N |
InChI: | InChI=1S/C6H5N3/c7-4-5-2-1-3-9-6(5)8/h1-3H,(H2,8,9) |
InChI Key: | YYXDQRRDNPRJFL-UHFFFAOYSA-N |
Boiling Point: | 297.6 °C at 760 mmHg |
Density: | 1.23 g/cm3 |
Appearance: | White crystalline powder |
MDL: | MFCD00128867 |
LogP: | 1.11668 |
GHS Hazard Statement: | H301 (16.67%): Toxic if swallowed [Danger Acute toxicity, oral] |
Precautionary Statement: | P264, P270, P280, P301+P310, P301+P312, P302+P352, P305+P351+P338, P310, P312, P321, P322, P330, P337+P313, P361, P363, P405, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
CN-113307765-A | Pyridine methylamine compound and preparation method thereof | 20210524 |
US-2021317114-A1 | Small molecule inhibitors of interleukin-4 | 20200320 |
WO-2021188871-A1 | Small molecule inhibitors of interleukin-4 | 20200320 |
US-2021292332-A1 | Heterocyclic Adenosine Receptor Antagonists | 20200316 |
WO-2021178347-A1 | Etching solution for titanium nitride and molybdenum conductive metal lines | 20200304 |
PMID | Publication Date | Title | Journal |
22530888 | 20120501 | CoMFA and CoMSIA studies of 1,2-dihydropyridine derivatives as anticancer agents | Medicinal chemistry (Shariqah (United Arab Emirates)) |
22590001 | 20120401 | 2-(Piperidin-1-yl)-6-(1H-pyrrol-1-yl)pyridine-3,5-dicarbonitrile | Acta crystallographica. Section E, Structure reports online |
22259462 | 20120101 | 6'-Bromo-1'H-spiro-[cyclo-hexane-1,2'-pyrido[2,3-d]pyrimidin]-4'(3'H)-one | Acta crystallographica. Section E, Structure reports online |
21522766 | 20101208 | 2-Amino-4-(4-fluoro-phen-yl)-6-(naphthalen-1-yl)pyridine-3-carbonitrile | Acta crystallographica. Section E, Structure reports online |
21588651 | 20100818 | Spiro-[cyclo-pentane-1,2'(1'H)-pyrido[2,3-d]pyrimidin]-4'(3'H)-one | Acta crystallographica. Section E, Structure reports online |
Complexity: | 135 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 119.048347172 |
Formal Charge: | 0 |
Heavy Atom Count: | 9 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 119.048347172 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 62.7 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 0.8 |
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Nitrogen Compounds
Pyridines
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