2-Amino-3,5-dichloropyridine - CAS 4214-74-8
Catalog: |
BB025058 |
Product Name: |
2-Amino-3,5-dichloropyridine |
CAS: |
4214-74-8 |
Synonyms: |
3,5-dichloropyridin-2-amine |
IUPAC Name: | 3,5-dichloropyridin-2-amine |
Description: | 2-Amino-3,5-dichloropyridine (CAS# 4214-74-8) is a useful research chemical. |
Molecular Weight: | 163.00 |
Molecular Formula: | C5H4Cl2N2 |
Canonical SMILES: | C1=C(C=NC(=C1Cl)N)Cl |
InChI: | InChI=1S/C5H4Cl2N2/c6-3-1-4(7)5(8)9-2-3/h1-2H,(H2,8,9) |
InChI Key: | OCWBGKZFOYMCCN-UHFFFAOYSA-N |
Boiling Point: | 235.2 °C at 760 mmHg |
Melting Point: | 79-83 °C |
Purity: | 98 % |
Density: | 1.497 g/cm3 |
Appearance: | Light beige to grey crystalline powder or flakes |
Storage: | Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. |
MDL: | MFCD00006313 |
LogP: | 2.55180 |
GHS Hazard Statement: | H302 (15.22%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
US-2020407344-A1 | Compounds for the treatment of braf-associated diseases and disorders | 20190628 |
WO-2020261156-A1 | Quinazolin-4-one derivatives useful for the treatment of braf-associated diseases and disorders | 20190628 |
US-2020270257-A1 | Chemical Compounds | 20190130 |
WO-2020160075-A1 | Chemical compounds | 20190130 |
CN-108675955-B | Preparation method of 2-amino-5 chloropyridine | 20180627 |
PMID | Publication Date | Title | Journal |
21754596 | 20110601 | Tetra-μ-acetato-κO:O'-bis-[(2-amino-3,5-dichloro-pyridine-κN)copper(II)](Cu-Cu) | Acta crystallographica. Section E, Structure reports online |
21754447 | 20110501 | 3-Chloro-pyridin-2-amine | Acta crystallographica. Section E, Structure reports online |
20023875 | 20091221 | Transition metal complexes of 2-amino-3,5-dihalopyridines: Syntheses, structures and magnetic properties of (3,5-diCAPH)2CuX4 and (3,5-diBAPH)2CuX4 | Dalton transactions (Cambridge, England : 2003) |
Complexity: | 99 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 161.9751535 |
Formal Charge: | 0 |
Heavy Atom Count: | 9 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 161.9751535 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 38.9 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1.8 |
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