2-Amino-3,5-dibromopyrazine - CAS 24241-18-7
Catalog: |
BB018382 |
Product Name: |
2-Amino-3,5-dibromopyrazine |
CAS: |
24241-18-7 |
Synonyms: |
3,5-dibromopyrazin-2-amine |
IUPAC Name: | 3,5-dibromopyrazin-2-amine |
Description: | 2-Amino-3,5-dibromopyrazine (CAS# 24241-18-7) is used in the preparation of conjugated polymers for neurotoxin detection. 2-Amino-3,5-dibromopyrazine is an intermediate in the preparation of rho kinase (ROCK) inhibitors. |
Molecular Weight: | 252.89 |
Molecular Formula: | C4H3Br2N3 |
Canonical SMILES: | C1=C(N=C(C(=N1)N)Br)Br |
InChI: | InChI=1S/C4H3Br2N3/c5-2-1-8-4(7)3(6)9-2/h1H,(H2,7,8) |
InChI Key: | DTLBKXRFWUERQN-UHFFFAOYSA-N |
Boiling Point: | 294.6 °C at 760 mmHg |
Purity: | 98 % |
Density: | 2.287 g/cm3 |
Appearance: | White to light yellow crystal powde |
MDL: | MFCD00673150 |
LogP: | 2.16500 |
GHS Hazard Statement: | H301 (83.33%): Toxic if swallowed [Danger Acute toxicity, oral] |
Precautionary Statement: | P261, P264, P270, P271, P280, P301+P310, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
CN-113480545-A | Imidazopyrazinone compound and preparation method and application thereof | 20210716 |
CN-113480543-A | 2,6, 8-polysubstituted imidazo [1,2-a ] pyrazine and synthetic method and application thereof | 20210707 |
CN-112574218-A | Synthesis method of indole or azabenzopyrrole compound | 20201230 |
WO-2021195403-A1 | Deuterated sgc stimulators | 20200326 |
US-2021292332-A1 | Heterocyclic Adenosine Receptor Antagonists | 20200316 |
PMID | Publication Date | Title | Journal |
20936789 | 20101111 | Aminopyrazine inhibitors binding to an unusual inactive conformation of the mitotic kinase Nek2: SAR and structural characterization | Journal of medicinal chemistry |
Complexity: | 99.8 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 252.86732 |
Formal Charge: | 0 |
Heavy Atom Count: | 9 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 250.86937 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 51.8 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1.5 |
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Amines and Anilines
Pyrazines
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