2-Amino-1-[3-(trifluoromethoxy)phenyl]ethanol - CAS 852392-18-8
Catalog: |
BB037553 |
Product Name: |
2-Amino-1-[3-(trifluoromethoxy)phenyl]ethanol |
CAS: |
852392-18-8 |
Synonyms: |
2-amino-1-[3-(trifluoromethoxy)phenyl]ethanol; 2-amino-1-[3-(trifluoromethoxy)phenyl]ethanol |
IUPAC Name: | 2-amino-1-[3-(trifluoromethoxy)phenyl]ethanol |
Description: | 2-Amino-1-[3-(trifluoromethoxy)phenyl]ethanol (CAS# 852392-18-8) is used as a reagent in the synthesis of potent and selective ethanolamine inhibitors of bacterial phenylalanyl tRNA synthetase. It is also used as a reagent in the synthesis of 1-aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase. |
Molecular Weight: | 221.18 |
Molecular Formula: | C9H10F3NO2 |
Canonical SMILES: | C1=CC(=CC(=C1)OC(F)(F)F)C(CN)O |
InChI: | InChI=1S/C9H10F3NO2/c10-9(11,12)15-7-3-1-2-6(4-7)8(14)5-13/h1-4,8,14H,5,13H2 |
InChI Key: | AQGZPXKBMIKDGM-UHFFFAOYSA-N |
LogP: | 3.19980 |
Publication Number | Title | Priority Date |
CA-2714743-A1 | Aryl-hydroxyethylamino-pyrimidines and triazines as modulators of fatty acid amide hydrolase | 20080219 |
EP-2254415-A1 | Aryl-hydroxyethylamino-pyrimidines and triazines as modulators of fatty acid amide hydrolase | 20080219 |
EP-2254415-B1 | Aryl-hydroxyethylamino-pyrimidines and triazines as modulators of fatty acid amide hydrolase | 20080219 |
US-2009264429-A1 | Aryl - Hydroxyethylamino - Pyrimidines and Triazines as Modulators of Fatty Acid amide Hydrolase | 20080219 |
US-8598202-B2 | Aryl-hydroxyethylamino-pyrimidines and triazines as modulators of fatty acid amide hydrolase | 20080219 |
Complexity: | 198 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 221.06636305 |
Formal Charge: | 0 |
Heavy Atom Count: | 15 |
Hydrogen Bond Acceptor Count: | 6 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 221.06636305 |
Rotatable Bond Count: | 3 |
Topological Polar Surface Area: | 55.5 |
Undefined Atom Stereocenter Count: | 1 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1.3 |
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