Inquiry Basket
| IUPAC Name: | [(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-diacetyloxy-15-[(2R,3S)-3-benzamido-3-phenyl-2-triethylsilyloxypropanoyl]oxy-1-hydroxy-10,14,17,17-tetramethyl-11-oxo-9-triethylsilyloxy-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate |
| Description: | 2',7-Bis(triethylsilyl)paclitaxel is a Paclitaxel (P132500) related compound which is an antineoplastic. Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma. Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. 2',7-Bis(triethylsilyl)paclitaxel is used in the preparation of paclitaxel from 10-deacetylpaclitaxel via regioselective silylation, acetylation and desilylation. |
| Molecular Weight: | 1082.43 |
| Molecular Formula: | C59H79NO14Si2 |
| Canonical SMILES: | CC[Si](CC)(CC)OC1CC2C(CO2)(C3C1(C(=O)C(C4=C(C(CC(C3OC(=O)C5=CC=CC=C5)(C4(C)C)O)OC(=O)C(C(C6=CC=CC=C6)NC(=O)C7=CC=CC=C7)O[Si](CC)(CC)CC)C)OC(=O)C)C)OC(=O)C |
| InChI: | InChI=1S/C59H79NO14Si2/c1-13-75(14-2,15-3)73-44-34-45-58(36-68-45,72-39(9)62)50-52(71-54(65)42-32-26-21-27-33-42)59(67)35-43(37(7)46(56(59,10)11)48(69-38(8)61)51(63)57(44,50)12)70-55(66)49(74-76(16-4,17-5)18-6)47(40-28-22-19-23-29-40)60-53(64)41-30-24-20-25-31-41/h19-33,43-45,47-50,52,67H,13-18,34-36H2,1-12H3,(H,60,64)/t43-,44-,45+,47-,48+,49+,50-,52-,57+,58-,59+/m0/s1 |
| InChI Key: | WPGSFSCXNLAODB-SDXTULIHSA-N |
| Melting Point: | 138-140°C |
| Solubility: | Chloroform (Slightly), Ethanol (Slightly) |
| Appearance: | White to Off-White Solid |
| Storage: | -20°C, Inert atmosphere |
| References: | Letourneau, P.C., et al. J. Cell Biol., 98, 1355 (1984); Manfredi, J.J., et al. Pharmacol. Ther., 25, 83 (1984); Danesi, R., et al. Mol. Pharmacol., 47, 1106 (1995); Markman, M., et al. Expert. Opin. Pharmacother., 3, 755 (2002); Stone, G.W., et al. N. Engl. J. Med., 350, 221 (2004); Lee, N. Y., Cho. J. S., Repub. Korean Kongkae Taeho Kongbo (2013), KR 2013035731 A 20130409. |
Catalog: BB012925
6-(Dimethylamino)-2-naphthaldehyde
Detail
![Cucurbit[5]uril](https://resource.bocsci.com/structure/259886-49-2.gif)
Catalog: BB076899
Cucurbit[5]uril
Detail
Catalog: BB054808
2-(4-Aminooxan-3-yl)acetic Acid
Detail
Catalog: BB014781
1,4-Benzodioxane-6-carbonitrile
Detail
Catalog: BB002009
Ethylenesulfate
Detail
![4-chloro-6-methylimidazo[2,1-f][1,2,4]triazine](https://resource.bocsci.com/structure/2090251-00-4.gif)
Catalog: BB016398
4-chloro-6-methylimidazo[2,1-f][1,2,4]triazine
Detail
Catalog: BB016397
1-methyl-3-(1,3-thiazol-2-yl)-1H-pyrazole-5-carbaldehyde
Detail
Catalog: BB054100
Azetidine
Detail
Customer Support
If the product you need is not in our catalog, please contact us in time to submit your needs. You can help our website get better and better. Why not submit the request today?
Customer Centered
Global Delivery
Warehouses in multiple cities to ensure fast delivery
Quality Assurance
Strict process parameter control to ensure product quality
Large Stock
> 20,000 building blocks and intermediates from stock
Process Scale-up
Process scale-up from lab to industrial scale
Flexible Batch Size
Flexible batch size for diverse industrial demandsRelated Functional Groups
Other Building Blocks
Customers Also Viewed
Estra-1,3,5(10)-triene-3,17-diol,7-(9-bromononyl)-,17-acetate,(7a,17b)-
Copyright © 2024 BOC Sciences. All rights reserved.
Our Products
