2,6-Difluoro-4-methoxybenzaldehyde - CAS 256417-10-4
Catalog: |
BB018986 |
Product Name: |
2,6-Difluoro-4-methoxybenzaldehyde |
CAS: |
256417-10-4 |
Synonyms: |
2,6-difluoro-4-methoxybenzaldehyde |
IUPAC Name: | 2,6-difluoro-4-methoxybenzaldehyde |
Description: | 2,6-Difluoro-4-methoxybenzaldehyde (CAS# 256417-10-4) is a versatile building block used for the synthesis of more complex pharmaceutical and biologically active compounds. It is shown to be involved in the preparation of potent and orally available G protein-coupled receptor 40 agonists, used the treatment of type 2 diabetes. |
Molecular Weight: | 172.13 |
Molecular Formula: | C8H6F2O2 |
Canonical SMILES: | COC1=CC(=C(C(=C1)F)C=O)F |
InChI: | InChI=1S/C8H6F2O2/c1-12-5-2-7(9)6(4-11)8(10)3-5/h2-4H,1H3 |
InChI Key: | ZYABCGOTMDPUDD-UHFFFAOYSA-N |
Boiling Point: | 207.1 °C at 760 mmHg |
Density: | 1.289 g/cm3 |
MDL: | MFCD04114368 |
LogP: | 1.78590 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
WO-2021108023-A1 | Penicillin-binding protein inhibitors | 20191126 |
WO-2020135771-A1 | Heterocyclic compound intermediate, preparation method therefor and application thereof | 20181229 |
WO-2020102643-A1 | Synthetic processes for the production of 1-((3s,4r)-4-(2,6-difluoro-4-methoxyphenyl)-2-oxopyrrolidin-3-yl)-3-phenylurea | 20181116 |
JP-2020066633-A | 1-phenyl-2-phenylethane derivative | 20181023 |
JP-6700465-B2 | 1-phenyl-2-phenylethane derivative | 20181023 |
Complexity: | 151 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 172.03358575 |
Formal Charge: | 0 |
Heavy Atom Count: | 12 |
Hydrogen Bond Acceptor Count: | 4 |
Hydrogen Bond Donor Count: | 0 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 172.03358575 |
Rotatable Bond Count: | 2 |
Topological Polar Surface Area: | 26.3 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1.6 |
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