2,6-Dichloropyrazine - CAS 4774-14-5

Catalog:	BB026379
Product Name:	2,6-Dichloropyrazine
CAS:	4774-14-5
Synonyms:	2,6-dichloropyrazine

Technical Data

Safety and Hazards

Patents

Literatures

Computed Properties

IUPAC Name:	2,6-dichloropyrazine
Description:	2,6-Dichloropyrazine (CAS# 4774-14-5) is used in the preparation of pyrazine and pyridine compounds as ATR kinase inhibitors.
Molecular Weight:	148.98
Molecular Formula:	C4H2Cl2N2
Canonical SMILES:	C1=C(N=C(C=N1)Cl)Cl
InChI:	InChI=1S/C4H2Cl2N2/c5-3-1-7-2-4(6)8-3/h1-2H
InChI Key:	LSEAAPGIZCDEEH-UHFFFAOYSA-N
Boiling Point:	187.5 ℃ at 760 mmHg
Purity:	97.0 %
Density:	1.493 g/cm³
MDL:	MFCD00006125
LogP:	1.78340

Publication Number	Title	Priority Date
WO-2021066958-A1	Inhibitor of btk and mutants thereof	20191005
WO-2021067606-A1	Brm targeting compounds and associated methods of use	20191001
US-2021085677-A1	Shp2 phosphatase inhibitors and methods of making and using the same	20190924
WO-2021058595-A1	Herbicidal compounds	20190924
WO-2021060281-A1	Prostaglandin e2 receptor ep2/ep4 dual antagonist	20190924

PMID	Publication Date	Title	Journal
22421707	20120514	Carboxylic acid functionalized ortho-linked oxacalix[2]benzene[2]pyrazine: synthesis, structure, hydrogen bond and metal directed self-assembly	Dalton transactions (Cambridge, England : 2003)
21080634	20101217	Syntheses and properties of two-dimensional, dicationic nonlinear optical chromophores based on pyrazinyl cores	The Journal of organic chemistry
21200733	20071206	1,3,5-Tris(6-chloro-pyrazin-2-yl-oxy)benzene	Acta crystallographica. Section E, Structure reports online
16153749	20051201	Synthesis of 2,6-diphenylpyrazine derivatives and their DNA binding and cytotoxic properties	European journal of medicinal chemistry
11442404	20010713	Dimetalation of pyrazines. a one-pot synthesis of multisubstituted pyrazine C-nucleosides	The Journal of organic chemistry

Related Products

Online Inquiry

Name:

* Phone:

* Service & Products of Interested:

Project Description:

* Quantity:

* Email:

* Verification Code:

Customer Support

If the product you need is not in our catalog, please contact us in time to submit your needs. You can help our website get better and better. Why not submit the request today?

Submit Requirement

Customer Centered

Global Delivery

Warehouses in multiple cities to ensure fast delivery

Quality Assurance

Strict process parameter control to ensure product quality

Large Stock

> 20,000 building blocks and intermediates from stock

Process Scale-up

Process scale-up from lab to industrial scale

Flexible Batch Size

Flexible batch size for diverse industrial demands

Related Functional Groups

Pyrazines

[25680-58-4]
2-Ethyl-3-methoxypyrazine
[56423-63-3]
2-Bromopyrazine
[1869118-24-0]
Ethyl {5-[(4-methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-yl}carbamate
[41270-65-9]
2-Chloro-3-phenylpyrazine
[2034430-99-2]
4-amino-N-(5-chloropyrazin-2-yl)benzenesulfonamide hydrochloride
[94777-52-3]
1-(2-Pyrazinyl)ethanol

Customers Also Viewed

[1866059-82-6]
1,1,2,2-Tetrafluoro-3-methylsulfonylpropane
[852913-16-7]
N-[3,5-Bis(trifluoromethyl)phenyl]-N-[(8a,9S)-6-methoxy-9-cinchonanyl]thiourea
[4294-16-0]
N6-Benzyl Adenosine
[133407-82-6]
MG-132
[3735-92-0]
Methyl dimethyldithiocarbamate
[144222-34-4]
(1R,2R)-(-)-N-p-Tosyl-1,2-diphenylethylenediamine

INDUSTRY LEADERS TRUST OUR PRODUCTS

Phone

US & Canada (Toll free):

UK:

International:

E-mail & Fax

E-mail:

Fax:

Address

USA:

UK:

Our Products

Inquiry Basket

Loading ......

Delete selected Go to checkout

GHS Hazard Statement:	H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
Precautionary Statement:	P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word:	Warning

Complexity:	70.4
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	147.9595035
Formal Charge:	0
Heavy Atom Count:	8
Hydrogen Bond Acceptor Count:	2
Hydrogen Bond Donor Count:	0
Isotope Atom Count:	0
Monoisotopic Mass:	147.9595035
Rotatable Bond Count:	0
Topological Polar Surface Area:	25.8 Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	1.5