2,6-Dichloro-3H-pyrimidin-4-one - CAS 120977-94-8
Catalog: |
BB062882 |
Product Name: |
2,6-Dichloro-3H-pyrimidin-4-one |
CAS: |
120977-94-8 |
Synonyms: |
2,6-Dichloro-4(1H)-pyrimidinone; 2,6-Dichloro-4-oxodihydropyrimidine; 2,4-Dichloro-6-(hydroxy)pyrimidine; 2,6-Dichloropyrimidin-4(1H)-one |
IUPAC Name: | 2,4-dichloro-1H-pyrimidin-6-one |
Description: | 2,6-Dichloro-3h-pyrimidin-4-one can be used in the preparation of blocked dihydropteridines as neuronal nitric oxide synthase (nNOS) activators. It can also be useful in the structure- activity relationship study of 2-pyrazolylpyrimidinones with potential antitubercular activity. |
Molecular Weight: | 164.98 |
Molecular Formula: | C4H2Cl2N2O |
Canonical SMILES: | C1=C(N=C(NC1=O)Cl)Cl |
InChI: | InChI=1S/C4H2Cl2N2O/c5-2-1-3(9)8-4(6)7-2/h1H,(H,7,8,9) |
InChI Key: | PVXOAKRQJOOIQX-UHFFFAOYSA-N |
Melting Point: | 157 - 159°C |
Solubility: | DMSO (Slightly), Methanol (Slightly) |
Appearance: | White to Off-White Solid |
Storage: | 4°C, Inert atmosphere |
References: | McInnes, C. R.; et al. Pteridines, 20, 27 (2009); Soares de Melo, C., et al. J. Med. Chem., 64, 719 (2021). |
Complexity: | 209 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 163.9544181 |
Formal Charge: | 0 |
Heavy Atom Count: | 9 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 163.9544181 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 41.5Ų |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1.2 |
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