2,5-Dimethylpyrazine - CAS 123-32-0
Catalog: |
BB005659 |
Product Name: |
2,5-Dimethylpyrazine |
CAS: |
123-32-0 |
Synonyms: |
2,5-dimethylpyrazine |
IUPAC Name: | 2,5-dimethylpyrazine |
Description: | 2,5-Dimethylpyrazine (CAS# 123-32-0) is used as a reagent in the synthesis of bone-targeted proteasome inhibitors for multiple myeloma (MM). 2,5-Dimethylpyrazine is also used in the preparation of 3-Methyl-2,5-bis-(2-hydroxyethyl)pyrazine (M295340); a degredation product of Clavulanic Acid (C563750) which is a β-lactamase inhibitor, typically added to amoxicillin to increase its effectiveness. |
Molecular Weight: | 108.14 |
Molecular Formula: | C6H8N2 |
Canonical SMILES: | CC1=CN=C(C=N1)C |
InChI: | InChI=1S/C6H8N2/c1-5-3-8-6(2)4-7-5/h3-4H,1-2H3 |
InChI Key: | LCZUOKDVTBMCMX-UHFFFAOYSA-N |
Boiling Point: | 155 °C |
Melting Point: | 15°C |
Flash Point: | 63°C |
Density: | 0.99 g/cm3 |
Appearance: | Clear colorless to pale yellow liquid |
Storage: | Inert atmosphere, Room Temperature |
MDL: | MFCD00006147 |
LogP: | 1.09340 |
Refractive Index: | 1.491-1.493 |
Stability: | Stable under normal temperatures and pressures. |
Vapor Pressure: | 1.5 [mmHg] |
GHS Hazard Statement: | H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P264, P270, P301+P312, P330, and P501 |
Signal Word: | Warning |
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PMID | Publication Date | Title | Journal |
22972787 | 20120901 | Characterization of cocoa liquors by GC-MS and LC-MS/MS: focus on alkylpyrazines and flavanols | Journal of mass spectrometry : JMS |
22827023 | 20120501 | [Balance hypothesis of action of socially significant volatile chemosignals on reactivity of chromosome machinery of the bone marrow dividing cells in the house mouse Mus domesticus L] | Zhurnal evoliutsionnoi biokhimii i fiziologii |
22515239 | 20120401 | Volatile compounds of black cumin seeds (Nigella sativa L.) from microwave-heating and conventional roasting | Journal of food science |
22563480 | 20120101 | Functional evidence of multidrug resistance transporters (MDR) in rodent olfactory epithelium | PloS one |
22567971 | 20120101 | [Action of two pyrazine-containing chemosignals on cells of bone marrow and testes in male house mouse Mus musculus L] | Zhurnal evoliutsionnoi biokhimii i fiziologii |
Complexity: | 62.9 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 108.068748264 |
Formal Charge: | 0 |
Heavy Atom Count: | 8 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 0 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 108.068748264 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 25.8 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 0.6 |
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