2,5-Dibromopyridine - CAS 624-28-2

Name: 2,5-Dibromopyridine
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog:	BB031586
Product Name:	2,5-Dibromopyridine
CAS:	624-28-2
Synonyms:	Pyridine, 2,5-dibromo-; 3,6-Dibromopyridine; NSC 76597

Technical Data

IUPAC Name:	2,5-dibromopyridine
Description:	2,5-Dibromopyridine is a chemical compound that finds applications primarily in pharmaceuticals, agrochemicals, and materials science. It serves as an important intermediate in the synthesis of various pharmaceutical agents, including those with potential anticancer, antiviral, and antibacterial properties. In the agrochemical industry, it is used as a building block for the production of pesticides and herbicides, aiding in effective pest and weed management. Additionally, 2,5-dibromopyridine is utilized in materials science for the development of advanced materials, such as polymers and liquid crystals, due to its unique bromine substituents. Its versatility and importance in these fields underscore its value in diverse scientific and industrial applications.
Molecular Weight:	236.89
Molecular Formula:	C5H3Br2N
Canonical SMILES:	C1=CC(=NC=C1Br)Br
InChI:	InChI=1S/C5H3Br2N/c6-4-1-2-5(7)8-3-4/h1-3H
InChI Key:	ZHXUWDPHUQHFOV-UHFFFAOYSA-N
Boiling Point:	235.7±20.0°C at 760 mmHg
Melting Point:	94-95°C (sublm)
Purity:	≥95%
Density:	1.633-1.635 g/cm3
Solubility:	Soluble in Chloroform (Slightly), Methanol (Slightly)
Appearance:	White to Off-white Solid
Storage:	Store at -20°C
MDL:	MFCD00006221
LogP:	2.60660

GHS Hazard Statement:	H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
Precautionary Statement:	P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word:	Warning

Publication Number	Title	Priority Date
CN-113248471-A	Preparation method of zolamide drug intermediate and intermediate thereof	20210705
CN-113248471-B	Preparation method of zolamide drug intermediate and intermediate thereof	20210705
CN-113354620-A	Efficient preparation method of tedizolid intermediate and intermediate thereof	20210705
CN-113461603-A	Synthetic method of medicine raw material 2, 5-dibromopyridine	20210701
CN-113354575-A	Synthesis method of terbinafine	20210607

PMID	Publication Date	Title	Journal
21739971	20110819	General and modular synthesis of isomeric 5-substituted pyridin-2-yl and 6-substituted pyridin-3-yl C-ribonucleosides bearing diverse alkyl, aryl, hetaryl, amino, carbamoyl, and hydroxy groups	The Journal of organic chemistry
21706084	20110807	Facile synthesis and platinum complexes of 4',5,5''-trisubstituted-2,2':6',2''-terpyridines	Dalton transactions (Cambridge, England : 2003)
21222493	20110204	Synthesis of di-, tri-, and tetrasulfides through multifold carbon-sulfur cross-coupling reactions with indium tri(organothiolates) in a one-pot procedure	The Journal of organic chemistry
20957086	20100908	Synthesis and characterization of a heteroleptic Ru(II) complex of phenanthroline containing oligo-anthracenyl carboxylic acid moieties	International journal of molecular sciences
21582562	20090325	2,5-Dibromo-pyridine	Acta crystallographica. Section E, Structure reports online

Complexity:	76.8
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	236.86117
Formal Charge:	0
Heavy Atom Count:	8
Hydrogen Bond Acceptor Count:	1
Hydrogen Bond Donor Count:	0
Isotope Atom Count:	0
Monoisotopic Mass:	234.86322
Rotatable Bond Count:	0
Topological Polar Surface Area:	12.9 Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	2.6