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| Description: | 2-(4-Nitro-1,3-dioxoisoindolin-2-yl)pentanedioic Acid is an intermediate in the synthesis of Pomalidomide (P688200), a thalidomide derivative and a potent inhibitor of TNF-α production. It is an antiinflammatory and antitumor agent used in the treatment of multiple myeloma. |
| Molecular Weight: | 322.23 |
| Molecular Formula: | C13H10N2O8 |
| Solubility: | DMF; Methanol |
| Appearance: | Yellow Solid |
| References: | Ruchelman, A. et al. Bioorg. Med. Chem. Lett., 23, 360 (2013); Latif, T. et al. Exp. Hematol. Oncol., 1, 27 (2012); Man, H. et al. Bioorg. Med. Chem. Lett., 13, 3415 (2003); Muller, G. et al. Bioorg. Med. Chem. Lett., 9, 1625 (1999). |
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