2-(4-Fluorophenyl)cyclopropanamine Hydrochloride - CAS 879324-66-0

Name: 2-(4-Fluorophenyl)cyclopropanamine Hydrochloride
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog:	BB038682
Product Name:	2-(4-Fluorophenyl)cyclopropanamine Hydrochloride
CAS:	879324-66-0
Synonyms:	2-(4-fluorophenyl)-1-cyclopropanamine;hydrochloride; 2-(4-fluorophenyl)cyclopropan-1-amine;hydrochloride

Technical Data

IUPAC Name:	2-(4-fluorophenyl)cyclopropan-1-amine;hydrochloride
Description:	2-(4-Fluorophenyl)cyclopropanamine Hydrochloride (CAS# 879324-66-0) is a synthetic intermediate in the preparation of thiazolinone 4-monosubstituted quinolines as CDK1-Cyclin B inhibitors for use as anti-cancer agents.
Molecular Weight:	187.64
Molecular Formula:	C9H11ClFN
Canonical SMILES:	C1C(C1N)C2=CC=C(C=C2)F.Cl
InChI:	InChI=1S/C9H10FN.ClH/c10-7-3-1-6(2-4-7)8-5-9(8)11;/h1-4,8-9H,5,11H2;1H
InChI Key:	ZQPBZLHQLCAFOQ-UHFFFAOYSA-N
LogP:	3.14260

Publication Number	Title	Priority Date
AU-2017263361-A1	Cyclopropyl-amide compounds as dual LSD1/HDAC inhibitors	20160509
CA-3022561-A1	Cyclopropyl-amide compounds as dual lsd1/hdac inhibitors	20160509
EP-3455204-A1	Cyclopropyl-amide compounds as dual lsd1/hdac inhibitors	20160509
JP-2019521082-A	Cyclopropyl-amide compounds as LSD1 / HDAC dual inhibitors	20160509
KR-20190005838-A	As dual LSD1 / HDAC inhibitors cyclopropyl-amide compounds	20160509

Complexity:	141
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	2
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	187.0564052
Formal Charge:	0
Heavy Atom Count:	12
Hydrogen Bond Acceptor Count:	2
Hydrogen Bond Donor Count:	2
Isotope Atom Count:	0
Monoisotopic Mass:	187.0564052
Rotatable Bond Count:	1
Topological Polar Surface Area:	26
Undefined Atom Stereocenter Count:	2
Undefined Bond Stereocenter Count:	0