2,4-Dichloro-7-methoxyquinazoline - CAS 62484-31-5
Catalog: |
BB031618 |
Product Name: |
2,4-Dichloro-7-methoxyquinazoline |
CAS: |
62484-31-5 |
Synonyms: |
2,4-dichloro-7-methoxyquinazoline; 2,4-dichloro-7-methoxyquinazoline |
IUPAC Name: | 2,4-dichloro-7-methoxyquinazoline |
Description: | 2,4-Dichloro-7-methoxyquinazoline (CAS# 62484-31-5) is a useful reactant for the preparation of 2, 4-diaminoquinazoline derivatives which is being study for a potential to be a potent PAK4 inhibitors. |
Molecular Weight: | 229.06 |
Molecular Formula: | C9H6Cl2N2O |
Canonical SMILES: | COC1=CC2=C(C=C1)C(=NC(=N2)Cl)Cl |
InChI: | InChI=1S/C9H6Cl2N2O/c1-14-5-2-3-6-7(4-5)12-9(11)13-8(6)10/h2-4H,1H3 |
InChI Key: | DJLGBZOLTZXCHN-UHFFFAOYSA-N |
Boiling Point: | 244.4 °C at 760 mmHg |
Density: | 1.45 g/cm3 |
MDL: | MFCD09954881 |
LogP: | 2.94520 |
GHS Hazard Statement: | H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
WO-2021130638-A1 | Diacylglycerol kinase modulating compounds | 20191224 |
WO-2020140001-A1 | Quinazoline derivatives as ectonucleotide pyrophosphatase phosphodiesterase 1 inhibitors | 20181228 |
WO-2020108613-A1 | Heteroaromatic derivatives for use as regulator, preparation method therefor and use thereof | 20181130 |
CN-111511738-A | Heteroaromatic derivative regulator, preparation method and application thereof | 20181130 |
TW-202033519-A | Heteroaromatic derivative regulator, its preparation method and application | 20181130 |
Complexity: | 205 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 227.9857182 |
Formal Charge: | 0 |
Heavy Atom Count: | 14 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 0 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 227.9857182 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 35 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 3.4 |
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Quinazolines
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