2,4-Dichloro-7-fluoroquinazoline - CAS 174566-15-5
Catalog: |
BB013024 |
Product Name: |
2,4-Dichloro-7-fluoroquinazoline |
CAS: |
174566-15-5 |
Synonyms: |
2,4-dichloro-7-fluoroquinazoline; 2,4-dichloro-7-fluoroquinazoline |
IUPAC Name: | 2,4-dichloro-7-fluoroquinazoline |
Description: | 2,4-Dichloro-7-fluoroquinazoline (CAS# 174566-15-5) is used in preparation of piperazine derivatives as MAGL inhibitors. |
Molecular Weight: | 217.03 |
Molecular Formula: | C8H3Cl2FN2 |
Canonical SMILES: | C1=CC2=C(C=C1F)N=C(N=C2Cl)Cl |
InChI: | InChI=1S/C8H3Cl2FN2/c9-7-5-2-1-4(11)3-6(5)12-8(10)13-7/h1-3H |
InChI Key: | HHGKYNUUYMRIAV-UHFFFAOYSA-N |
Boiling Point: | 277 °C |
Density: | 1.571 g/cm3 |
LogP: | 3.07570 |
Publication Number | Title | Priority Date |
WO-2021130638-A1 | Diacylglycerol kinase modulating compounds | 20191224 |
CN-111247129-A | Piperazine derivatives as MAGL inhibitors | 20171010 |
TW-201922728-A | Novel heterocyclic compounds | 20171010 |
WO-2019072785-A1 | PIPERAZINE DERIVATIVES AS MAGL INHIBITORS | 20171010 |
EP-3694840-A1 | Piperazine derivatives as magl inhibitors | 20171010 |
PMID | Publication Date | Title | Journal |
22412620 | 20120301 | 2,4-Dichloro-7-fluoro-quinazoline | Acta crystallographica. Section E, Structure reports online |
Complexity: | 193 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 215.9657317 |
Formal Charge: | 0 |
Heavy Atom Count: | 13 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 0 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 215.9657317 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 25.8 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 3.6 |
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