2,4-Dichloro-6-morpholinopyrimidine - CAS 52127-83-0
Catalog: |
BB027719 |
Product Name: |
2,4-Dichloro-6-morpholinopyrimidine |
CAS: |
52127-83-0 |
Synonyms: |
4-(2,6-dichloro-4-pyrimidinyl)morpholine; 4-(2,6-dichloropyrimidin-4-yl)morpholine |
IUPAC Name: | 4-(2,6-dichloropyrimidin-4-yl)morpholine |
Description: | A reactant used in the preparation of α-azinylalkylamino-substituted pyrimidines as JAK2 inhibitors. |
Molecular Weight: | 234.08 |
Molecular Formula: | C8H9Cl2N3O |
Canonical SMILES: | C1COCCN1C2=CC(=NC(=N2)Cl)Cl |
InChI: | InChI=1S/C8H9Cl2N3O/c9-6-5-7(12-8(10)11-6)13-1-3-14-4-2-13/h5H,1-4H2 |
InChI Key: | QGGYMWHOBGSQCF-UHFFFAOYSA-N |
Boiling Point: | 396.137 °C at 760 mmHg |
Density: | 1.435 g/cm3 |
Solubility: | Other solvents(Soluble) : Toluene |
Appearance: | Solid |
LogP: | 1.68500 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, and P362 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
WO-2021081375-A1 | Inhibitors of raf kinases | 20191024 |
US-11098031-B1 | Inhibitors of RAF kinases | 20191024 |
US-2021300904-A1 | Inhibitors of raf kinases | 20191024 |
WO-2020009971-A1 | Pikfyve inhibitors | 20180705 |
AU-2019299234-A1 | PIKfyve inhibitors | 20180705 |
Complexity: | 189 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 233.0122673 |
Formal Charge: | 0 |
Heavy Atom Count: | 14 |
Hydrogen Bond Acceptor Count: | 4 |
Hydrogen Bond Donor Count: | 0 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 233.0122673 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 38.2 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 2.2 |
-
Catalog: BB001891
2,5-Dimethylmorpholine
Detail
-
Catalog: BB026817
N,N'-Dicyclohexyl-4-morpholinecarboxamidine
Detail
-
Catalog: BB018658
N-Cyclohexyl-N'-(2-morpholinoethyl)carbodiimide methyl-p-toluenesulfonate
Detail
-
Catalog: BB002238
N-Ethyl-2-morpholin-4-ylethanamine
Detail
-
Catalog: BB007746
2,4-Dimorpholinonitrobenzene
Detail
-
Catalog: BB009127
4-(4-Bromo-2,6-difluorophenyl)morpholine
Detail
-
Catalog: BB022035
Morpholine-2,2,3,3,5,5,6,6-D8
Detail
-
Catalog: BB015440
4-(5-Bromo-2-pyridyl)morpholine
Detail
Online Inquiry
Customer Support
Customer Centered
Related Functional Groups
Morpholines/Thiomorpholines
Customers Also Viewed
INDUSTRY LEADERS TRUST OUR PRODUCTS