2,4-Dichloro-6-morpholinopyrimidine - CAS 52127-83-0

Catalog:	BB027719
Product Name:	2,4-Dichloro-6-morpholinopyrimidine
CAS:	52127-83-0
Synonyms:	4-(2,6-dichloro-4-pyrimidinyl)morpholine; 4-(2,6-dichloropyrimidin-4-yl)morpholine

Technical Data

Safety and Hazards

Patents

Computed Properties

IUPAC Name:	4-(2,6-dichloropyrimidin-4-yl)morpholine
Description:	A reactant used in the preparation of α-azinylalkylamino-substituted pyrimidines as JAK2 inhibitors.
Molecular Weight:	234.08
Molecular Formula:	C8H9Cl2N3O
Canonical SMILES:	C1COCCN1C2=CC(=NC(=N2)Cl)Cl
InChI:	InChI=1S/C8H9Cl2N3O/c9-6-5-7(12-8(10)11-6)13-1-3-14-4-2-13/h5H,1-4H2
InChI Key:	QGGYMWHOBGSQCF-UHFFFAOYSA-N
Boiling Point:	396.137 °C at 760 mmHg
Density:	1.435 g/cm³
Solubility:	Other solvents(Soluble) : Toluene
Appearance:	Solid
LogP:	1.68500

Publication Number	Title	Priority Date
WO-2021081375-A1	Inhibitors of raf kinases	20191024
US-11098031-B1	Inhibitors of RAF kinases	20191024
US-2021300904-A1	Inhibitors of raf kinases	20191024
WO-2020009971-A1	Pikfyve inhibitors	20180705
AU-2019299234-A1	PIKfyve inhibitors	20180705

Related Products

Online Inquiry

Name:

* Phone:

* Service & Products of Interested:

Project Description:

* Quantity:

* Email:

* Verification Code:

Customer Support

If the product you need is not in our catalog, please contact us in time to submit your needs. You can help our website get better and better. Why not submit the request today?

Submit Requirement

Customer Centered

Global Delivery

Warehouses in multiple cities to ensure fast delivery

Quality Assurance

Strict process parameter control to ensure product quality

Large Stock

> 20,000 building blocks and intermediates from stock

Process Scale-up

Process scale-up from lab to industrial scale

Flexible Batch Size

Flexible batch size for diverse industrial demands

Related Functional Groups

Morpholines/Thiomorpholines

[23588-51-4]
2,2-Dimethyl-3-morpholin-4-ylpropanal
[1170406-61-7]
2-Morpholino-1-(1,3,5-trimethyl-1H-pyrazol-4-yl)ethanone
[1005586-29-7]
Ethyl 1-methyl-3-(morpholin-4-ylcarbonyl)pyrazole-5-carboxylate
[6976-49-4]
Ethyl morpholine-4-carboxylate
[1152749-21-7]
Morpholino(1H-pyrazol-4-yl)methanone
[1185683-82-2]
N-(3-Morpholin-4-ylpropyl)butan-1-amine oxalic acid

GHS Hazard Statement:	H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
Precautionary Statement:	P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, and P362
Signal Word:	Warning

Complexity:	189
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	233.0122673
Formal Charge:	0
Heavy Atom Count:	14
Hydrogen Bond Acceptor Count:	4
Hydrogen Bond Donor Count:	0
Isotope Atom Count:	0
Monoisotopic Mass:	233.0122673
Rotatable Bond Count:	1
Topological Polar Surface Area:	38.2 Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	2.2