IUPAC Name: | 2-[3-(difluoromethyl)-6-fluoro-2-oxo-1H-pyridin-4-yl]acetic acid |
Description: | 2-[3-(Difluoromethyl)-6-fluoro-2-hydroxypyridin-4-yl]acetic acid is a building block of Favipiravir (F103350). Favipiravir is used for the treatment of advanced Ebola virus infection in a small animal models. |
Molecular Weight: | 221.13 |
Molecular Formula: | C8H6F3NO3 |
Canonical SMILES: | C1=C(NC(=O)C(=C1CC(=O)O)C(F)F)F |
InChI: | InChI=1S/C8H6F3NO3/c9-4-1-3(2-5(13)14)6(7(10)11)8(15)12-4/h1,7H,2H2,(H,12,15)(H,13,14) |
InChI Key: | RTAKBRPDUYBELA-UHFFFAOYSA-N |
References: | Oestereich, L., et al. Antiviral Res., 105, 17 (2014); Baranovich, T., et al. J. Virol. 87, 3741 (2013); Chem. and Eng. News p.8, Dec. 1 (2014). |
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Other Building Blocks
N-((4-Oxo-1-phenyl-4,7-dihydro-1H-pyrazolo[3,4-d]pyrimidin-6-yl)methyl)acetamide
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