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| IUPAC Name: | 1-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione |
| Description: | 2',3'-Dideoxy-3'-fluorouridine is a reactant used in the synthesis of 5'-trityl nucleosides to inhibit Plasmodium falciparum dUTPase. It exhibits anti-retrovirus activity. |
| Molecular Weight: | 230.19 |
| Molecular Formula: | C9H11FN2O4 |
| Canonical SMILES: | C1C(C(OC1N2C=CC(=O)NC2=O)CO)F |
| InChI: | InChI=1S/C9H11FN2O4/c10-5-3-8(16-6(5)4-13)12-2-1-7(14)11-9(12)15/h1-2,5-6,8,13H,3-4H2,(H,11,14,15)/t5-,6+,8+/m0/s1 |
| InChI Key: | BKIUEHLYJFLWPK-SHYZEUOFSA-N |
| Melting Point: | 190-192 ℃ |
| Purity: | ≥ 95 % |
| Density: | 1.50±0.1 g/cm3 (Predicted) |
| Solubility: | Soluble in Aqueous Base (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly), Water |
| Appearance: | White to off-white solid |
| Storage: | Store at -20 ℃ |
| MDL: | MFCD00192015 |
| LogP: | -0.84550 |
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Fluorinated Building Blocks
[(2,3-Difluorophenyl)methyl][(1,3-dimethylpyrazol-4-yl)methyl]amine
3-(1',3'-Dimethyl-5-(trifluoromethyl)-1'H,2H-[3,4'-bipyrazol]-2-yl)propanenitrile
5-Cyclopropyl-1-(4-nitrophenyl)-3-(trifluoromethyl)-1H-pyrazole
Other Pyrimidines
2-Morpholino-2-(2-(trifluoromethyl)pyrimidin-5-yl)ethanamine
5-Phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid
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