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| Description: | 2,2-Dichloro-3-(dimethylphenylsilyl)-cyclobutanone is an intermediate used in synthesizing 2-Cyclobutenyl-3-trifluoromethyl-5-chloro-1H-indole-1-carboxylic Acid Ethyl Ester, which is synthesized from 5-chloro-2-oxindole (C375030), that is used in the preparation of novel GSK-3β inhibitors as anticancer agents. |
| Molecular Weight: | 273.23 |
| Molecular Formula: | C12H14Cl2OSi |
| Solubility: | Dichloromethane, Ether, Ethyl Acetate |
| Appearance: | Colorless Oil |
| References: | Choi, M.J., et al. Bull. Korean. Chem. Soc., 32, 2015 (2011); Otani, M., et al. Bioorg. Med. Chem. Lett.. 20, 4259 (2010); Jhan, Y.H., et al. Tetrahedron. Lett., 54, 1155 (2013); Hsieh, J.C., et al. Org. Biomolec. Chem., 10, 6404 (2012). |
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