IUPAC Name: | 2-(2-chloropyridin-4-yl)-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one |
Description: | 2-(2-Chloropyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one is used to prepare pyrrolopyridine Inhibitors of Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MK-2). It is also used to synthesize heteroaryl-substituted pyrrolopyridinones and analogs as cdc7 kinase inhibitors and potential antitumor agents. |
Molecular Weight: | 247.68 |
Molecular Formula: | C12H10ClN3O |
Canonical SMILES: | C1CNC(=O)C2=C1NC(=C2)C3=CC(=NC=C3)Cl |
InChI: | InChI=1S/C12H10ClN3O/c13-11-5-7(1-3-14-11)10-6-8-9(16-10)2-4-15-12(8)17/h1,3,5-6,16H,2,4H2,(H,15,17) |
InChI Key: | JTRXEPCDEVNYPE-UHFFFAOYSA-N |
Melting Point: | >275°C (dec.) |
Solubility: | DMSO (Slightly), Methanol (Slightly, Sonicated) |
Appearance: | Off-White to Pale Beige Solid |
Storage: | Refrigerator |
References: | Anderson, D., et al. J. Med. Chem., 50, 2647 (2007); Vanotti, E., et al. J. Med. Chem., 51, 487 (2008). |
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