2-(2-Chloroethoxy)ethanol - CAS 628-89-7
Catalog: |
BB031868 |
Product Name: |
2-(2-Chloroethoxy)ethanol |
CAS: |
628-89-7 |
Synonyms: |
2-(2-chloroethoxy)ethanol |
Application: |
2-(2-Chloroethoxy)ethanol is a degradation product of Bis(2-Chloroethyl) Ether. 2-(2-Chloroethoxy)ethanol is a potential genotoxic impurity (PGI) in active pharmaceutical ingredients (APIs). |
IUPAC Name: | 2-(2-chloroethoxy)ethanol |
Description: | 2-(2-Chloroethoxy)ethanol is a degradation product of Bis(2-Chloroethyl) Ether. |
Molecular Weight: | 124.57 |
Molecular Formula: | C4H9ClO2 |
Canonical SMILES: | C(COCCCl)O |
InChI: | InChI=1S/C4H9ClO2/c5-1-3-7-4-2-6/h6H,1-4H2 |
InChI Key: | LECMBPWEOVZHKN-UHFFFAOYSA-N |
Boiling Point: | 180-185 °C |
Purity: | > 95 % |
Density: | 1.18 g/cm3 |
Appearance: | Clear colourless to pale yellow oil |
MDL: | MFCD00002870 |
LogP: | 0.23410 |
GHS Hazard Statement: | H315 (93.59%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
CN-112939892-A | Preparation method of quetiapine | 20210323 |
CN-112778162-A | Preparation method of chiral beta- (Boc-amino) -5-hexynoic acid | 20210106 |
CN-214020708-U | Synthesizer of 2-chloroethoxy ethanol | 20201211 |
CN-112386710-A | Method for improving pterostilbene water solubility by using embedding technology | 20201209 |
CN-112473396-A | Anion exchange membrane material for diffusion dialysis acid recovery and preparation method thereof | 20201127 |
PMID | Publication Date | Title | Journal |
21485288 | 20110301 | Validation of GC method for quantitative determination of residual 2-(2-chloroethoxy)ethanol (CEE) and N-methyl-2-pyrrolidinone (NMP) in pharmaceutical active substance | Acta poloniae pharmaceutica |
19908697 | 20091201 | A study on the photopolymerization of acrylic monomers having fluorene moiety for the application of holographic data storage system | Journal of nanoscience and nanotechnology |
17665871 | 20070301 | GC method for quantitative determination of residual 2-(2-chloroethoxy) ethanol (CEE) and N-methyl-2-pyrrolidinone (NMP) in quetiapine | Acta poloniae pharmaceutica |
Complexity: | 32.9 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 124.0291072 |
Formal Charge: | 0 |
Heavy Atom Count: | 7 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 124.0291072 |
Rotatable Bond Count: | 4 |
Topological Polar Surface Area: | 29.5 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 0 |
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