Fenclozic acid - CAS 17969-20-9

Name: Fenclozic acid
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog:	BB013597
Product Name:	Fenclozic acid
CAS:	17969-20-9
Synonyms:	2-(2-(4-Chlorophenyl)thiazol-4-yl)acetic acid; Myalex; Acidum fenclozicum; ICI 54450; 2-(p-Chlorophenyl)-4-thiazoleacetic acid

Technical Data

Patents

Literatures

Computed Properties

IUPAC Name:	2-[2-(4-chlorophenyl)-1,3-thiazol-4-yl]acetic acid
Description:	Fenclozic acid is an analgesic and antipyretic with anti-inflammatory properties.
Molecular Weight:	253.70
Molecular Formula:	C11H8ClNO2S
Canonical SMILES:	C1=CC(=CC=C1C2=NC(=CS2)CC(=O)O)Cl
InChI:	InChI=1S/C11H8ClNO2S/c12-8-3-1-7(2-4-8)11-13-9(6-16-11)5-10(14)15/h1-4,6H,5H2,(H,14,15)
InChI Key:	APBSKHYXXKHJFK-UHFFFAOYSA-N
Boiling Point:	444.7 °C at 760 mmHg
Density:	1.434 g/cm³
MDL:	MFCD00721754
LogP:	3.09060

Related Products

Online Inquiry

Name:

* Phone:

* Service & Products of Interested:

Project Description:

* Quantity:

* Email:

* Verification Code:

Customer Support

If the product you need is not in our catalog, please contact us in time to submit your needs. You can help our website get better and better. Why not submit the request today?

Submit Requirement

Customer Centered

Global Delivery

Warehouses in multiple cities to ensure fast delivery

Quality Assurance

Strict process parameter control to ensure product quality

Large Stock

> 20,000 building blocks and intermediates from stock

Process Scale-up

Process scale-up from lab to industrial scale

Flexible Batch Size

Flexible batch size for diverse industrial demands

Related Functional Groups

Carbonyl Compounds

[89908-23-6]C23H22N2O5
2-Propenoic acid, 2-(3',3'-dimethyl-6-nitrospiro[2H-1-benzopyran-2,2'-[2H]indol]-1'(3'H)-yl)ethyl ester
[5650-34-0]C9H8O2
Oxiran-2-yl(phenyl)methanone
[17746-05-3]C11H21ClO
Undecanoyl chloride
[1018141-88-2]C17H14N4O2
1-(2-Cyanoethyl)-3-methyl-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
[1006443-01-1]C9H6N4O4
1-(5-Nitropyridin-2-yl)-1H-pyrazole-3-carboxylic acid
[956439-56-8]C6H5N3O6
1-(Carboxymethyl)-3-nitro-1H-pyrazole-5-carboxylic acid

Publication Number	Title	Priority Date
WO-2021195403-A1	Deuterated sgc stimulators	20200326
WO-2021195011-A1	Immunomodulatory oligosaccharides for the treatment of viral respiratory infection	20200324
US-2021317079-A1	Tetralin and tetrahydroquinoline compounds as inhibitors of hif-2alpha	20200319
WO-2021188769-A1	Tetralin and tetrahydroquinoline compounds as inhibitors of hif-2alpha	20200319
US-10980756-B1	Methods of treatment	20200316

PMID	Publication Date	Title	Journal
24085192	20140101	A correlation between the in vitro drug toxicity of drugs to cell lines that express human P450s and their propensity to cause liver injury in humans	Toxicological sciences : an official journal of the Society of Toxicology
23609606	20130801	In vitro exploration of potential mechanisms of toxicity of the human hepatotoxic drug fenclozic acid	Archives of toxicology
22194678	20111201	Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps)	PLoS computational biology

Complexity:	256
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	252.9964274
Formal Charge:	0
Heavy Atom Count:	16
Hydrogen Bond Acceptor Count:	4
Hydrogen Bond Donor Count:	1
Isotope Atom Count:	0
Monoisotopic Mass:	252.9964274
Rotatable Bond Count:	3
Topological Polar Surface Area:	78.4
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	2.7