t-boc-N-amido-PEG3-alcohol - CAS 139115-92-7
Catalog: |
BB008895 |
Product Name: |
t-boc-N-amido-PEG3-alcohol |
CAS: |
139115-92-7 |
Synonyms: |
NHBoc-PEG3-OH; 2-[2-(2-t-Boc-aminoethoxy]ethoxy]ethanol; N-[2-[2-(2-Hydroxyethoxy)ethoxy]ethyl]carbamic Acid 1,1-Dimethylethyl Ester; 2-[2-(2-tert-Butyloxycarbonylaminoethoxy)ethoxy]ethanol; Boc-NH-PEG3; Carbamic acid, N-[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]-, 1,1-dimethylethyl ester; 2-Methyl-2-propanyl {2-[2-(2-hydroxyethoxy)ethoxy]ethyl}carbamate; Boc-NH-PEG3-OH; N-Boc-PEG3-alcohol |
Related CAS: | 159156-95-3 (polymer)
|
IUPAC Name: | tert-butyl N-[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]carbamate |
Description: | Boc-NH-PEG3 is a PROTAC linker, which refers to the alkyl/ether composition. Boc-NH-PEG3 can be used in the synthesis of a series of PROTACs. Boc-NH-PEG3 is a PEG derivative containing a hydroxyl group and Boc-protected amino group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The Boc group can be deprotected under mild acidic conditions to form the free amine. |
Molecular Weight: | 249.30 |
Molecular Formula: | C11H23NO5 |
Canonical SMILES: | CC(C)(C)OC(=O)NCCOCCOCCO |
InChI: | InChI=1S/C11H23NO5/c1-11(2,3)17-10(14)12-4-6-15-8-9-16-7-5-13/h13H,4-9H2,1-3H3,(H,12,14) |
InChI Key: | FMLOTGGIHAYZLW-UHFFFAOYSA-N |
Boiling Point: | 374.6±27.0°C (Predicted) |
Purity: | >95% |
Density: | 1.071±0.06 g/cm3 (Predicted) |
Solubility: | Soluble in Chloroform (Slightly), Methanol (Slightly) |
Appearance: | Light Yellow Oily Liquid |
Storage: | Store at 2-8°C |
LogP: | 0.92750 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
KR-20210122708-A | HMG-CoA Reductase Degradation Inducing Compound | 20200330 |
WO-2021201577-A1 | Hmg-coa reductase degradation inducing compound | 20200330 |
WO-2021170109-A1 | Tropomyosin receptor kinase (trk) degradation compounds and methods of use | 20200226 |
WO-2021155317-A1 | Asgpr-binding compounds for the degradation of extracellular proteins | 20200131 |
CN-113214227-A | Heterocyclic compound and application thereof | 20200121 |
Complexity: | 203 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 249.15762283 |
Formal Charge: | 0 |
Heavy Atom Count: | 17 |
Hydrogen Bond Acceptor Count: | 5 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 249.15762283 |
Rotatable Bond Count: | 10 |
Topological Polar Surface Area: | 77 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | -0.1 |
-
Catalog: BB001442
(R)-3-Hydroxy-1-methylpyrrolidine
Detail
-
Catalog: BB002564
(5R,6R,7S,8R,8aS)-6,7,8-Trihydroxy-5-(hydroxymethyl)hexahydroimidazo[1,2-a]pyridine-2,3-dione
Detail
-
Catalog: BB000198
4-(Hydroxymethyl)-5-methylisoxazole
Detail
-
Catalog: BB000402
4-(Hydroxymethyl)benzaldehyde Oxime
Detail
-
Catalog: BB001769
Ethyl (R)-(-)-Mandelate
Detail
-
Catalog: BB001393
4-Chloro-5-(hydroxymethyl)-2-(methylthio)pyrimidine
Detail
-
Catalog: BB003852
(2R,4S,5R)-5-Hydroxy-2-phenyl-1,3-dioxane-4-methanol
Detail
-
Catalog: BB044030
3-Hydroxy-2-hexanone
Detail
Online Inquiry
Customer Support
Customer Centered
Related Functional Groups
Alcohols and Derivatives
Customers Also Viewed
INDUSTRY LEADERS TRUST OUR PRODUCTS