Azido-PEG2-amine - CAS 166388-57-4
Catalog: |
BB012278 |
Product Name: |
Azido-PEG2-amine |
CAS: |
166388-57-4 |
Synonyms: |
Azide-PEG3-Amine;2-[2-(2-Azidoethoxy)ethoxy]ethanamine; Azido-PEG2-C2-amine; N3-PEG2-CH2CH2NH2 |
Related CAS: | 749244-38-0
|
IUPAC Name: | 2-[2-(2-azidoethoxy)ethoxy]ethanamine |
Description: | Azido-PEG2-C2-amine (N3-PEG2-CH2CH2NH2) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG2-C2-amine is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
Molecular Weight: | 174.20 |
Molecular Formula: | C6H14N4O2 |
Canonical SMILES: | C(COCCOCCN=[N+]=[N-])N |
InChI: | InChI=1S/C6H14N4O2/c7-1-3-11-5-6-12-4-2-9-10-8/h1-7H2 |
InChI Key: | ZHWGWSYNZIZTFL-UHFFFAOYSA-N |
Purity: | ≥95% |
Solubility: | Soluble in Chloroform, Dichloromethane (Slightly) |
Appearance: | Yellow Oily Matter |
Storage: | Store at 2-8°C under inert atmosphere |
LogP: | 0.44166 |
GHS Hazard Statement: | H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] |
Precautionary Statement: | P260, P264, P280, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P363, P405, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
CN-112409436-A | Radionuclide-labeled estrogen receptor molecule targeting compound and application thereof | 20201106 |
WO-2021125255-A1 | Novel crosslinked alginic acid | 20191218 |
WO-2021125279-A1 | Chemically crosslinked alginate gel fiber | 20191218 |
WO-2021111185-A1 | Compositions and methods related to molecular conjugation | 20191202 |
CN-110790812-A | Reagent for detecting skin cholesterol and preparation method thereof | 20191108 |
PMID | Publication Date | Title | Journal |
22069757 | 20110901 | Impact of the nature and size of the polymeric backbone on the ability of heterobifunctional ligands to mediate shiga toxin and serum amyloid p component ternary complex formation | Toxins |
Complexity: | 136 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 174.11167570 |
Formal Charge: | 0 |
Heavy Atom Count: | 12 |
Hydrogen Bond Acceptor Count: | 5 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 174.11167570 |
Rotatable Bond Count: | 8 |
Topological Polar Surface Area: | 58.8 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | -0.1 |
Online Inquiry
Customer Support
Customer Centered
Related Functional Groups
Nitrogen Compounds
Customers Also Viewed
INDUSTRY LEADERS TRUST OUR PRODUCTS