2-(2-(2-(Prop-2-yn-1-yloxy)ethoxy)ethoxy)acetic acid - CAS 944561-46-0
Catalog: |
BB041332 |
Product Name: |
2-(2-(2-(Prop-2-yn-1-yloxy)ethoxy)ethoxy)acetic acid |
CAS: |
944561-46-0 |
Synonyms: |
Propargyl-PEG3-CH2COOH; Propargyl-PEG2-CH2COOH; Acetic acid, 2-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]-; 2-[2-[2-(2-Propyn-1-yloxy)ethoxy]ethoxy]acetic Acid; {2-[2-(2-Propyn-1-yloxy)ethoxy]ethoxy}acetic acid |
IUPAC Name: | 2-[2-(2-prop-2-ynoxyethoxy)ethoxy]acetic acid |
Description: | 2-(2-(2-(Prop-2-yn-1-yloxy)ethoxy)ethoxy)acetic acid is a polyethylene glycol (PEG)-based PROTAC linker that can be used in the synthesis of a series of PROTACs. |
Molecular Weight: | 202.20 |
Molecular Formula: | C9H14O5 |
Canonical SMILES: | C#CCOCCOCCOCC(=O)O |
InChI: | InChI=1S/C9H14O5/c1-2-3-12-4-5-13-6-7-14-8-9(10)11/h1H,3-8H2,(H,10,11) |
InChI Key: | FWONAGPFSKACQC-UHFFFAOYSA-N |
Boiling Point: | 334.9±27.0°C (Predicted) |
Purity: | ≥95% |
Density: | 1.158±0.06 g/cm3 (Predicted) |
Storage: | Store at 2-8°C |
LogP: | -0.24600 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P332+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
EP-3820532-A2 | Dimeric immuno-modulatory compounds against cereblon-based mechanisms | 20180711 |
WO-2017184995-A1 | Compounds that induce degradation of anti-apoptotic bcl-2 family proteins and the uses thereof | 20160421 |
US-2012308584-A1 | Protein-active agent conjugates and method for preparing the same | 20110508 |
US-2014161829-A1 | Antibody-active agent conjugates and methods of use | 20110508 |
US-2014187756-A1 | Methods of preparing antibody-active agent conjugates | 20110508 |
Complexity: | 193 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 202.08412354 |
Formal Charge: | 0 |
Heavy Atom Count: | 14 |
Hydrogen Bond Acceptor Count: | 5 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 202.08412354 |
Rotatable Bond Count: | 9 |
Topological Polar Surface Area: | 65 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | -0.5 |
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