(1S,2R)-(+)-Norephedrine Hydrochloride
Catalog: |
BB076650 |
Product Name: |
(1S,2R)-(+)-Norephedrine Hydrochloride |
Synonyms: |
(αS)-α-[(1R)-1-Aminoethyl]benzenemethanol Hydrochloride; (+)-(1S,2R)-Norephedrine Hydrochloride; (+)-Norephedrin Hydrochloride; (+)-Norephedrine Hydrochloride; (+)-Phenylpropanolamine Hydrochloride; (1R,2S)-2-Hydroxy-2-phenyl-1-methyl-1-aminoethane Hydrochloride; (1S,2R)-(+)-Norephedrine Hydrochloride; (1S,2R)-2-Amino-1-phenyl-1-propanol Hydrochloride; (1S,2R)-2-Amino-1-phenylpropan-1-ol Hydrochloride;(1S,2R)-2-Amino-1-phenylpropanol Hydrochloride; (1S,2R)-2-Methyl-1-phenyl-2-aminoethanol Hydrochloride; (1S,2R)-Norephedrine Hydrochloride; (2R,3S)-3-Phenyl-3-hydroxy-2-aminopropane Hydrochloride;D-(+)-Norephedrine Hydrochloride; d-Norephedrine Hydrochloride; d-Phenylpropanolamine Hydrochloride |
IUPAC Name: | (1S,2R)-2-amino-1-phenylpropan-1-olhydrochloride |
Description: | (1S,2R)-(+)-Norephedrine Hydrochloride is used in preparation of pyrrolopyridines as ERK inhibitors useful in treatment of diseases. |
Molecular Weight: | 151.21 + (36.46) |
Molecular Formula: | C9H13NO·HCl |
Canonical SMILES: | CC(C(C1=CC=CC=C1)O)N.Cl |
InChI: | InChI=1S/C9H13NO.ClH/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7,9,11H,10H2,1H31H/t7-,9-/m1./s1 |
InChI Key: | DYWNLSQWJMTVGJ-PRCZDLBKSA-N |
Melting Point: | 381 to 385 °F |
Solubility: | Greater than or equal to 100 mg/ml at 70 °f |
Appearance: | Phenylpropanolamine hydrochloride is an odorless white to creamy-white crystalline powder. Bitter taste. Ph (3% solution):4.5-6. Ph (10% solution) 4.2-5.5. (ntp, 1992) |
References: | Slamon, D., et al.:PCT Int. Appl., (2020). |
GHS Hazard Statement: | H302 (97.08%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P264, P270, P301+P317, P330, and P501 |
Signal Word: | Warning |
Complexity: | 110 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 2 |
Defined Atom Stereocenter Count: | 2 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 187.0763918 |
Formal Charge: | 0 |
Heavy Atom Count: | 12 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 3 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 187.0763918 |
Rotatable Bond Count: | 2 |
Topological Polar Surface Area: | 46.2Ų |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
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