(1S,2R)-(+)-Norephedrine Hydrochloride

Name: (1S,2R)-(+)-Norephedrine Hydrochloride
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog:	BB076650
Product Name:	(1S,2R)-(+)-Norephedrine Hydrochloride
Synonyms:	(αS)-α-[(1R)-1-Aminoethyl]benzenemethanol Hydrochloride; (+)-(1S,2R)-Norephedrine Hydrochloride; (+)-Norephedrin Hydrochloride; (+)-Norephedrine Hydrochloride; (+)-Phenylpropanolamine Hydrochloride; (1R,2S)-2-Hydroxy-2-phenyl-1-methyl-1-aminoethane Hydrochloride; (1S,2R)-(+)-Norephedrine Hydrochloride; (1S,2R)-2-Amino-1-phenyl-1-propanol Hydrochloride; (1S,2R)-2-Amino-1-phenylpropan-1-ol Hydrochloride;(1S,2R)-2-Amino-1-phenylpropanol Hydrochloride; (1S,2R)-2-Methyl-1-phenyl-2-aminoethanol Hydrochloride; (1S,2R)-Norephedrine Hydrochloride; (2R,3S)-3-Phenyl-3-hydroxy-2-aminopropane Hydrochloride;D-(+)-Norephedrine Hydrochloride; d-Norephedrine Hydrochloride; d-Phenylpropanolamine Hydrochloride

Technical Data

IUPAC Name:	(1S,2R)-2-amino-1-phenylpropan-1-olhydrochloride
Description:	(1S,2R)-(+)-Norephedrine Hydrochloride is used in preparation of pyrrolopyridines as ERK inhibitors useful in treatment of diseases.
Molecular Weight:	151.21 + (36.46)
Molecular Formula:	C9H13NO·HCl
Canonical SMILES:	CC(C(C1=CC=CC=C1)O)N.Cl
InChI:	InChI=1S/C9H13NO.ClH/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7,9,11H,10H2,1H31H/t7-,9-/m1./s1
InChI Key:	DYWNLSQWJMTVGJ-PRCZDLBKSA-N
Melting Point:	381 to 385 °F
Solubility:	Greater than or equal to 100 mg/ml at 70 °f
Appearance:	Phenylpropanolamine hydrochloride is an odorless white to creamy-white crystalline powder. Bitter taste. Ph (3% solution):4.5-6. Ph (10% solution) 4.2-5.5. (ntp, 1992)
References:	Slamon, D., et al.:PCT Int. Appl., (2020).

GHS Hazard Statement:	H302 (97.08%): Harmful if swallowed [Warning Acute toxicity, oral]
Precautionary Statement:	P264, P270, P301+P317, P330, and P501
Signal Word:	Warning

Complexity:	110
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	2
Defined Atom Stereocenter Count:	2
Defined Bond Stereocenter Count:	0
Exact Mass:	187.0763918
Formal Charge:	0
Heavy Atom Count:	12
Hydrogen Bond Acceptor Count:	2
Hydrogen Bond Donor Count:	3
Isotope Atom Count:	0
Monoisotopic Mass:	187.0763918
Rotatable Bond Count:	2
Topological Polar Surface Area:	46.2Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0