(1S,2R)-2-Amino-1,2-diphenylethanol - CAS 23364-44-5

Name: (1S,2R)-2-Amino-1,2-diphenylethanol
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog:	BB018020
Product Name:	(1S,2R)-2-Amino-1,2-diphenylethanol
CAS:	23364-44-5
Synonyms:	(1S,2R)-2-amino-1,2-diphenylethanol; (1S,2R)-2-amino-1,2-diphenylethanol

Technical Data

IUPAC Name:	(1S,2R)-2-amino-1,2-diphenylethanol
Description:	(1S,2R)-(+)-2-Amino-1,2-diphenylethanol are potent and selective inhibitors of Histone deacetylase-3.
Molecular Weight:	213.28
Molecular Formula:	C14H15NO
Canonical SMILES:	C1=CC=C(C=C1)C(C(C2=CC=CC=C2)O)N
InChI:	InChI=1S/C14H15NO/c15-13(11-7-3-1-4-8-11)14(16)12-9-5-2-6-10-12/h1-10,13-14,16H,15H2/t13-,14+/m1/s1
InChI Key:	GEJJWYZZKKKSEV-KGLIPLIRSA-N
Boiling Point:	374.3 °C at 760 mmHg
Melting Point:	142-144 °C
Purity:	≥ 98 %, ≥ 95 % e.e.
Density:	1.148 g/cm³
Appearance:	White or off-white crystalline powder
Storage:	Room temperature.
MDL:	MFCD00074959
LogP:	3.12030

GHS Hazard Statement:	H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
Precautionary Statement:	P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word:	Warning

Publication Number	Title	Priority Date
CN-112321538-A	Method for synthesizing monoamine-protected piperazine- (R/S) 2-formate	20201028
CN-110483369-B	Method for synthesizing (7S) -5-azaspiro [2.4] heptane-7-radical carbamic acid tert-butyl ester	20190912
US-2020361855-A1	Tetrahydro-1h-cyclopenta[cd]indene derivatives as hypoxia inducible factor-2(alpha) inhibitors	20190418
TW-202104174-A	Tetrahydro-1h-cyclopenta[cd]indene derivatives as hypoxia inducible factor-2(alpha) inhibitors	20190418
US-2021246102-A1	Tetrahydro-1h-cyclopenta[cd]indene derivatives as hypoxia inducible factor-2(alpha) inhibitors	20190418

PMID	Publication Date	Title	Journal
19319988	20100101	Synthesis of dendrimer-type chiral stationary phases based on the selector of (1S,2R)-(+)-2-amino-1,2-diphenylethanol derivate and their enantioseparation evaluation by HPLC	Chirality
19345586	20090501	NMDA receptor affinities of 1,2-diphenylethylamine and 1-(1,2-diphenylethyl)piperidine enantiomers and of related compounds	Bioorganic & medicinal chemistry
18655165	20090401	Immobilization of (1S,2R)-(+)-2-amino-1,2-diphenylethanol derivates on aminated silica gel with different linkages as chiral stationary phases and their enantioseparation evaluation by HPLC	Chirality
11722198	20011130	Asymmetric synthesis of [2,3-(13)C(2),(15)N]-4-benzyloxy-5,6-diphenyl-2,3,5,6-tetrahydro-4H-oxazine-2-one via lipase TL-mediated kinetic resolution of benzoin: general procedure for the synthesis of [2,3-(13)C(2),(15)N]-L-alanine	The Journal of organic chemistry
11322546	20010316	Solid-phase synthesis of homogeneous ruthenium catalysts on silica for the continuous asymmetric transfer hydrogenation reaction	Chemistry (Weinheim an der Bergstrasse, Germany)

Complexity:	195
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	2
Defined Bond Stereocenter Count:	0
Exact Mass:	213.115364102
Formal Charge:	0
Heavy Atom Count:	16
Hydrogen Bond Acceptor Count:	2
Hydrogen Bond Donor Count:	2
Isotope Atom Count:	0
Monoisotopic Mass:	213.115364102
Rotatable Bond Count:	3
Topological Polar Surface Area:	46.2 Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	1.3