![(1R,4R)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-cyclopentene-1-carboxylic Acid Methyl Ester](https://resource.bocsci.com/structure/168958-19-8.gif)
Inquiry Basket
| IUPAC Name: | methyl (1R,4R)-4-[(2-methylpropan-2-yl)oxycarbonylamino]cyclopent-2-ene-1-carboxylate |
| Description: | (1R,4R)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-cyclopentene-1-carboxylic Acid Methyl Ester is an intermediate in synthesizing trans-Abacavir Dihydrochloride (A104995), which is an impurity of Abacavir. Abacavir (A104990) is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. |
| Molecular Weight: | 241.28 |
| Molecular Formula: | C12H19NO4 |
| Canonical SMILES: | CC(C)(C)OC(=O)NC1CC(C=C1)C(=O)OC |
| InChI: | InChI=1S/C12H19NO4/c1-12(2,3)17-11(15)13-9-6-5-8(7-9)10(14)16-4/h5-6,8-9H,7H2,1-4H3,(H,13,15)/t8-,9-/m0/s1 |
| InChI Key: | HKLDTKMTZPXEAZ-IUCAKERBSA-N |
| Solubility: | Methanol |
| Storage: | Room Temperature, under inert atmosphere |
Catalog: BB000560
6(5H)-Phenanthridinone
Detail
Catalog: BB054600
3-glycidoxypropyltrimethoxysilane
Detail
Catalog: BB054100
Azetidine
Detail
Catalog: BB006975
(3R)-N-methyloxolan-3-amine hydrochloride
Detail
![4-chloro-6-methylimidazo[2,1-f][1,2,4]triazine](https://resource.bocsci.com/structure/2090251-00-4.gif)
Catalog: BB016398
4-chloro-6-methylimidazo[2,1-f][1,2,4]triazine
Detail
Catalog: BB014781
1,4-Benzodioxane-6-carbonitrile
Detail
Catalog: BB054808
2-(4-Aminooxan-3-yl)acetic Acid
Detail
Catalog: BB077194
(S)-(-)-1,2-epoxydecane
Detail
Customer Support
If the product you need is not in our catalog, please contact us in time to submit your needs. You can help our website get better and better. Why not submit the request today?
Customer Centered
Global Delivery
Warehouses in multiple cities to ensure fast delivery
Quality Assurance
Strict process parameter control to ensure product quality
Large Stock
> 20,000 building blocks and intermediates from stock
Process Scale-up
Process scale-up from lab to industrial scale
Flexible Batch Size
Flexible batch size for diverse industrial demandsRelated Functional Groups
Other Building Blocks
Customers Also Viewed
Copyright © 2024 BOC Sciences. All rights reserved.
Our Products
