(1R,3S,5R)-5-Methyl-2-azabicyclo[3.1.0]hexane-2,3-dicarboxylic acid 2-tert-butyl ester - CAS 1306734-44-0

Catalog: BB060106
Product Name: (1R,3S,5R)-5-Methyl-2-azabicyclo[3.1.0]hexane-2,3-dicarboxylic acid 2-tert-butyl ester
CAS: 1306734-44-0
Synonyms: (1R,3S,5R)-2-(tert-butoxycarbonyl)-5-methyl-2-azabicyclo[3.1.0]hexane-3-carboxylic Acid
(1R,3S,5R)-5-Methyl-2-azabicyclo[3.1.0]hexane-2,3-dicarboxylic acid 2-tert-butyl ester
IUPAC Name:(1R,3S,5R)-5-methyl-2-[(2-methylpropan-2-yl)oxycarbonyl]-2-azabicyclo[3.1.0]hexane-3-carboxylic acid
Description:(1R,3S,5R)-5-Methyl-2-azabicyclo[3.1.0]hexane-2,3-dicarboxylic acid 2-tert-butyl ester can be used to prepare indole analogs as complement factor D inhibitors for treating age-related macular degeneration. It can also be utilized to synthesize hepatitis C virus inhibitors.
Molecular Weight:241.28
Molecular Formula:C12H19NO4
Canonical SMILES:CC12CC(N(C1C2)C(=O)OC(C)(C)C)C(=O)O
InChI:InChI=1S/C12H19NO4/c1-11(2,3)17-10(16)13-7(9(14)15)5-12(4)6-8(12)13/h7-8H,5-6H2,1-4H3,(H,14,15)/t7-,8+,12-/m0/s1
InChI Key:ITNAYTUVWAOJPY-SXMVTHIZSA-N
References:Altmann, E., et al. PCT Int. Appl. WO 2012093101 A1 20120712 (2012); Lavoie, R., et al.: PCT Int. Appl. WO 2011059887 A1 20110519 (2011); Pack, S. K., et al.: PCT Int. Appl. WO 2011059850 A1 2011051 (2011).

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