(1R,3R)-3-Methoxycyclobutan-1-amine Hydrochloride - CAS 1363381-00-3
Catalog: |
BB057869 |
Product Name: |
(1R,3R)-3-Methoxycyclobutan-1-amine Hydrochloride |
CAS: |
1363381-00-3 |
Synonyms: |
3-METHOXYCYCLOBUTANAMINE; CIS-3-METHOXYCYCLOBUTANAMINE; TRANS-3-METHOXYCYCLOBUTANAMINE; 3-methoxycyclobutan-1-amine; (1S,3S)-3-METHOXYCYCLOBUTAN-1-AMINE; trans-3-Methoxycyclobutan-1-amine |
IUPAC Name: | 3-methoxycyclobutan-1-amine |
Description: | (1R,3R)-3-Methoxycyclobutan-1-amine Hydrochloride (CAS# 1363381-00-3) is used to prepare dihydrofuropyridines as Rho-kinase inhibitors which can be used in treatment of Rho-kinase mediated diseases. In addition, it can also be used as a reactant for preparation of 1-oxo-phthalazin-2-ylacetamides as NLRP3 modulators. |
Molecular Weight: | 136.6 |
Molecular Formula: | C5H11NO·HCl |
Canonical SMILES: | COC1CC(C1)N |
InChI: | InChI=1S/C5H11NO/c1-7-5-2-4(6)3-5/h4-5H,2-3,6H2,1H3 |
InChI Key: | CTZHBPUHGUPFSN-UHFFFAOYSA-N |
References: | Rancati, F., et al. PCT Int. Appl., 113 (2022); Craig, R. A., et al. PCT Int. Appl., 204 (2022).. |
GHS Hazard Statement: | H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P260, P261, P264, P270, P271, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P330, P362+P364, P363, P405, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
WO-2022048631-A1 | Compound having antitumor activity and use thereof | 20200904 |
WO-2021202775-A1 | N-(heterocyclyl and heterocyclylalkyl)-3-benzylpyridin-2-amine derivatives as sstr4 agonists | 20200331 |
TW-202130630-A | Glp-1r modulating compounds | 20191025 |
TW-202126657-A | Substituted pyrazolopyrimidines as irak4 inhibitors | 20191002 |
WO-2020123395-A1 | 2-oxoquinazoline derivatives as methionine adenosyltransferase 2a inhibitors | 20181210 |
AU-2019395338-A1 | 2-oxoquinazoline derivatives as methionine adenosyltransferase 2A inhibitors | 20181210 |
BR-112021010842-A2 | 2-Oxoquinazoline Derivatives as Methionine Adenosyltransferase 2a Inhibitors | 20181210 |
CA-3121236-A1 | 2-oxoquinazoline derivatives as methionine adenosyltransferase 2a inhibitors | 20181210 |
CN-113166078-A | 2-oxoquinazoline derivatives as methionine adenosyltransferase 2A inhibitors | 20181210 |
EP-3894396-A1 | 2-oxoquinazoline derivatives as methionine adenosyltransferase 2a inhibitors | 20181210 |
Complexity: | 59.1 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 101.084063974 |
Formal Charge: | 0 |
Heavy Atom Count: | 7 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 101.084063974 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 35.2Ų |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | -0.2 |
Online Inquiry
Customer Support
Customer Centered
Related Functional Groups
Other Building Blocks
Customers Also Viewed
INDUSTRY LEADERS TRUST OUR PRODUCTS