1H-Pyrazolo[3,4-b]pyridine - CAS 271-73-8
Catalog: |
BB019489 |
Product Name: |
1H-Pyrazolo[3,4-b]pyridine |
CAS: |
271-73-8 |
Synonyms: |
7-Aza-1H-indazole; 7-Azaindazole; Pyrazolo[3,4-b]pyridine |
IUPAC Name: | 1H-pyrazolo[3,4-b]pyridine |
Description: | A pyrazole derivative as a kinase inhibitor. |
Molecular Weight: | 119.12 |
Molecular Formula: | C6H5N3 |
Canonical SMILES: | C1=CC2=C(NN=C2)N=C1 |
InChI: | InChI=1S/C6H5N3/c1-2-5-4-8-9-6(5)7-3-1/h1-4H,(H,7,8,9) |
InChI Key: | GVLRTOYGRNLSDW-UHFFFAOYSA-N |
Boiling Point: | 110-120°C at 0.1 Torr |
Melting Point: | 98-99°C |
Purity: | ≥95% |
Density: | 1.38±0.1 g/cm3 |
Solubility: | Soluble in Chloroform, Ethyl Acetate |
Appearance: | Pale Orange Solid |
Storage: | Store at 2-8°C |
MDL: | MFCD05663981 |
LogP: | 0.95790 |
GHS Hazard Statement: | H302 (75%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
CN-111620868-A | Preparation method of 1H-pyrazolo [3,4-b ] pyridine-3-formaldehyde | 20200528 |
CN-111620868-B | Preparation method of 1H-pyrazolo [3,4-b ] pyridine-3-formaldehyde | 20200528 |
US-2021236663-A1 | Compounds and probes for imaging huntingtin protein | 20191218 |
WO-2021121282-A1 | Preparation and application of class of n-containing heterocyclic compounds with immunomodulatory function | 20191217 |
WO-2021113492-A1 | Cyclic compounds and methods of using same | 20191206 |
PMID | Publication Date | Title | Journal |
22968474 | 20120911 | Synthesis of a new series of pyridine and fused pyridine derivatives | Molecules (Basel, Switzerland) |
22178093 | 20120201 | Synthesis of pyrazolo[3,4-b]pyridines under microwave irradiation in multi-component reactions and their antitumor and antimicrobial activities - Part 1 | European journal of medicinal chemistry |
22167248 | 20120128 | Multicomponent approaches to 8-carboxylnaphthyl-functionalized pyrazolo[3,4-b]pyridine derivatives | Organic & biomolecular chemistry |
21723178 | 20120101 | Ultrasound assisted one-pot, three-components synthesis of pyrimido[1,2-a]benzimidazoles and pyrazolo[3,4-b]pyridines: A new access via phenylsulfone synthon | Ultrasonics sonochemistry |
22223281 | 20120101 | Hydrogen-bonded assembly in six closely related pyrazolo[3,4-b]pyridine derivatives; a simple chain, three types of chains of rings and a complex sheet structure | Acta crystallographica. Section C, Crystal structure communications |
Complexity: | 105 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 119.048347172 |
Formal Charge: | 0 |
Heavy Atom Count: | 9 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 119.048347172 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 41.6 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 0.8 |
Online Inquiry
Customer Support
Customer Centered
Related Functional Groups
Pyridines
Customers Also Viewed
INDUSTRY LEADERS TRUST OUR PRODUCTS