1H-Pyrazole-3-sulfonamide - CAS 1797158-84-9

Catalog:	BB061830
Product Name:	1H-Pyrazole-3-sulfonamide
CAS:	1797158-84-9
Synonyms:	1H-pyrazole-3-sulfonamide; 1H-pyrazole-5-sulfonamide; pyrazole-sulfonamide; 5-(sulfonamido)pyrazole

Technical Data

Safety and Hazards

Patents

Literatures

Computed Properties

IUPAC Name:	1H-pyrazole-5-sulfonamide
Description:	1H-Pyrazole-3-sulfonamide may be useful in the preparation of macrocycles as modulators of CFTR in the treatment of cystic fibrosis.
Molecular Weight:	147.15
Molecular Formula:	C3H5N3O2S
Canonical SMILES:	C1=C(NN=C1)S(=O)(=O)N
InChI:	InChI=1S/C3H5N3O2S/c4-9(7,8)3-1-2-5-6-3/h1-2H,(H,5,6)(H2,4,7,8)
InChI Key:	LSJVQKDTVCDSPE-UHFFFAOYSA-N
References:	Abela, A. R., et al. PCT Int. Appl., 983pp., WO 2021030556 (2021).

Publication Number	Title	Priority Date
CN-113045498-A	1, 5-diaryl pyrazole derivative, synthesis method and application	20210324
CN-111423376-A	Isopimaric acyl heterocyclic sulfonamide derivative and preparation method and application thereof	20200519
CN-111056978-A	Sulfonamide compound and preparation method and application thereof	20191213
CN-111056978-B	Sulfonamide compound and preparation method and application thereof	20191213
WO-2021030556-A1	Modulators of cystic fibrosis transmembrane conductance regulator	20190814
TW-202115094-A	Modulators of cystic fibrosis transmembrane conductance regulator	20190814
WO-2020210139-A1	Pyrazolesulfonamides as antitumor agents	20190410
EP-3953331-A1	Pyrazolesulfonamides as antitumor agents	20190410
CN-109633065-B	Method for detecting drug residues in animal body	20181228
WO-2020117493-A1	Method for preparing n-phenylpyrazole-1-carboxamides	20181203

PMID	Publication Date	Title	Journal
21190552	20101229	Amyloid precursor protein selective gamma-secretase inhibitors for treatment of Alzheimer's disease	Alzheimer's research & therapy

Related Products

Online Inquiry

Name:

* Phone:

* Service & Products of Interested:

Project Description:

* Quantity:

* Email:

* Verification Code:

Customer Support

If the product you need is not in our catalog, please contact us in time to submit your needs. You can help our website get better and better. Why not submit the request today?

Submit Requirement

Customer Centered

Global Delivery

Warehouses in multiple cities to ensure fast delivery

Quality Assurance

Strict process parameter control to ensure product quality

Large Stock

> 20,000 building blocks and intermediates from stock

Process Scale-up

Process scale-up from lab to industrial scale

Flexible Batch Size

Flexible batch size for diverse industrial demands

Related Functional Groups

Other Building Blocks

[79407-66-2]
3-(2,4-Dihydroxyphenyl)-2-propenal
[1195209-18-7]
H-Glu-nh2 Hydrochloride
[635319-09-4]
(3R,4R)-tert-Butyl 3-Hydroxy-4-(hydroxymethyl)pyrrolidine-1-carboxylate
[1450663-24-7]
(3R,4R)-tert-Butyl 4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidine-1-carboxylate
(2R,5S,10aS,10bS)-10b-Hydroxy-5-isopropyl-2-methyl-3,6-dioxooctahydro-2H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazine-2-carboxylic Acid
[773057-66-2]
(4-Aminobenzyl)phosphonic Acid Hydrochloride

GHS Hazard Statement:	H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
Precautionary Statement:	P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501
Signal Word:	Warning

Complexity:	182
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	147.01024758
Formal Charge:	0
Heavy Atom Count:	9
Hydrogen Bond Acceptor Count:	4
Hydrogen Bond Donor Count:	2
Isotope Atom Count:	0
Monoisotopic Mass:	147.01024758
Rotatable Bond Count:	1
Topological Polar Surface Area:	97.2Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	-0.9