1H-Indazole-7-carboxylic acid - CAS 677304-69-7
Catalog: |
BB033378 |
Product Name: |
1H-Indazole-7-carboxylic acid |
CAS: |
677304-69-7 |
Synonyms: |
1H-indazole-7-carboxylic acid |
IUPAC Name: | 1H-indazole-7-carboxylic acid |
Description: | 1H-Indazole-7-carboxylic acid (CAS# 677304-69-7) is an inhibitor of nitric oxide synthases. |
Molecular Weight: | 162.15 |
Molecular Formula: | C8H6N2O2 |
Canonical SMILES: | C1=CC2=C(C(=C1)C(=O)O)NN=C2 |
InChI: | InChI=1S/C8H6N2O2/c11-8(12)6-3-1-2-5-4-9-10-7(5)6/h1-4H,(H,9,10)(H,11,12) |
InChI Key: | WBCWIQCXHSXMDH-UHFFFAOYSA-N |
Boiling Point: | 443.7 °C at 760 mmHg |
Purity: | 97.0 % |
Density: | 1.506 g/cm3 |
MDL: | MFCD06804572 |
LogP: | 1.26110 |
GHS Hazard Statement: | H302 (16.67%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
US-2020102303-A1 | Monoacylglycerol Lipase Modulators | 20180928 |
US-2020102311-A1 | Monoacylglycerol Lipase Modulators | 20180928 |
WO-2020065613-A1 | Monoacylglycerol lipase modulators | 20180928 |
WO-2020065614-A1 | Monoacylglycerol lipase modulators | 20180928 |
WO-2019204523-A1 | Bicyclic carboxamides and methods of use thereof | 20180417 |
PMID | Publication Date | Title | Journal |
18502134 | 20080601 | Inhibitory effects of a series of 7-substituted-indazoles toward nitric oxide synthases: particular potency of 1H-indazole-7-carbonitrile | Bioorganic & medicinal chemistry |
Complexity: | 196 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 162.042927438 |
Formal Charge: | 0 |
Heavy Atom Count: | 12 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 162.042927438 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 66 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1.1 |
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