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| Description: | 12-epi Lubiprostone is an analog of Lubiprostone (L473500). Lubiprostone is a bicyclic fatty acid metabolite analog of Prostaglandin E1. It activates specific chloride channels in the gastrointestinal tract to stimulate intestinal fluid secretion, increase gastrointestinal transit, and improve symptoms of constipation. |
| Molecular Formula: | C20H32F2O5 |
| References: | Farthing, M., et al. Drugs, 56, 11 (1998), Pare, P., et al. Am. J. Gastroenterol., 96, 3130 (2001); Sloots, C., et al. Aliment. Pharmacol. Ther., 16, 759 (2002), Coremans, G., et al. Digestion, 67, 82 (2003). |
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