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Medicinal chemistry and drug research require diverse chemical components to meet strict requirements not only in terms of physical and chemical properties but also in terms of chemical reactivity.
Medicinal chemistry and drug research require diverse chemical components to meet strict requirements not only in terms of physical and chemical properties but also in terms of chemical reactivity.
The chemists use the 'build–couple–pair' strategy of organic synthesis, which entails preparing molecular building blocks that contain several chemical groups.
The chemical building block (CBB) is a molecule which can be converted to various secondary chemicals and intermediates, and, in turn, into a broad range of different downstream uses.
| Description: | 10-Undecen-1-ol (CAS# 112-43-6) is a selective heat shock protein 90 (Hsp90) inhibitor which can exert a potent anticancer activity. Studies demonstates that SNX-2112 can exhibit a potent anticancer activity against B16 melanoma cells both in vitro and in vivo, by inhibiting cell proliferation and inducing cell cycle arrest and apoptosis in a mechanism dependent on the degredation of Hsp90 client proteins. |
| Molecular Weight: | 170.29 |
| Molecular Formula: | C11H22O |
| Canonical SMILES: | C=CCCCCCCCCCO |
| InChI: | InChI=1S/C11H22O/c1-2-3-4-5-6-7-8-9-10-11-12/h2,12H,1,3-11H2 |
| InChI Key: | GIEMHYCMBGELGY-UHFFFAOYSA-N |
| Boiling Point: | 250.00 ℃ (EPI 4.0) |
| Purity: | 98.0 % |
| Density: | 0.846 g/cm3 |
| Solubility: | Insoluble in water; soluble in alcohol. |
| Appearance: | Colorless liquid |
| Storage: | Store tightly sealed under inert gas in a cool, well-ventilated area. |
| MDL: | MFCD00004750 |
| LogP: | 3.28550 |
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