IUPAC Name: | [1-(trifluoromethyl)cyclobutyl]methanaminehydrochloride |
Description: | [1-(Trifluoromethyl)cyclobutyl]methanamine Hydrochloride is a salt analog of [1-(Trifluoromethyl)cyclobutyl]methanamine (CAT# T898778), which may be useful in the preparation of thieno[2,3-d]pyrimidine-6-carboxamides as androgen receptor modulators for treatment of prostate cancer. [1-(Trifluoromethyl)cyclobutyl]methanamine may also be useful in the preparation of aminopyridinyl pyrazolecarboxamides as modulators of RORγt. |
Molecular Weight: | 153.15 + 36.46 |
Molecular Formula: | C6H10F3N·HCl |
Canonical SMILES: | C1CC(C1)(CN)C(F)(F)F.Cl |
InChI: | InChI=1S/C6H10F3N.ClH/c7-6(8,9)5(4-10)2-1-3-5/h1-4,10H21H |
InChI Key: | HSTWTAYNCJVTLY-UHFFFAOYSA-N |
References: | Mikochik, P., et al. PCT Int. Appl., 108pp. (2020); Goldberg, S., et al. U.S. Pat. Appl. Publ., 94pp. (2019); Goldberg, S., et al. PCT Int. Appl., 793pp. (2017). |
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