Description: | 1-(Trichloromethyl)-3,4-dihydro-1H-pyrido[3,4-b]indole-2(9H)-carbaldehyde is a proposed intermediate for the synthesis of (S)-1-Trichloromethyl-1,2,3,4-Tetrahydro-β-carboline (TaClo)(T774240), which is the S-enatiomer of the dopaminergic and serotonergic neurotoxin. Liver enzymes produces TaClo via catalysis reaction of Tricloroethane with Tryptamine (T894600). TaClo destroys dopamine-producing cells and is a molecule of importance in the study of Parkinson's disease. |
Molecular Weight: | 317.6 |
Molecular Formula: | C13H11Cl3N2O |
References: | Bringmann, G. et al. J. Chrom. B Anal. Technol. Biomed. Life, 767, 321 (2002); Bringmann, G. et al. Tetrahedron, 60, 8143 (2004). |
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