1-(tetrahydro-2-furoyl)-piperazine - CAS 63074-07-7
Catalog: |
BB031985 |
Product Name: |
1-(tetrahydro-2-furoyl)-piperazine |
CAS: |
63074-07-7 |
Synonyms: |
oxolan-2-yl(piperazin-1-yl)methanone |
IUPAC Name: | oxolan-2-yl(piperazin-1-yl)methanone |
Description: | 1-(Tetrahydro-2-furoyl)-piperazine (Terazosin EP Impurity N) has been used as a reactant for the preparation of pyrazol-3-propanoic acid derivatives as inhibitors of leukotriene biosynthesis in human neutrophils. |
Molecular Weight: | 184.24 |
Molecular Formula: | C9H16N2O2 |
Canonical SMILES: | C1CC(OC1)C(=O)N2CCNCC2 |
InChI: | InChI=1S/C9H16N2O2/c12-9(8-2-1-7-13-8)11-5-3-10-4-6-11/h8,10H,1-7H2 |
InChI Key: | UKESBLFBQANJHH-UHFFFAOYSA-N |
Boiling Point: | 140 °C (1.5 mmHg) |
Purity: | 95 % |
Density: | 1.147 g/cm3 |
Appearance: | Colorless to yellow viscous liquid |
MDL: | MFCD00190247 |
LogP: | -0.13610 |
GHS Hazard Statement: | H315 (12.77%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, and P362 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
WO-2020023355-A1 | Inhibitors of indoleamine 2,3-dioxygenase and methods of their use | 20180723 |
EP-3786156-A1 | 10h-phenothiazine ferroptosis inhibitor and preparation method therefor and application thereof | 20180427 |
US-2021040079-A1 | 10H-phenothiazine ferroptosis inhibitor as well as the preparative method and the use thereof | 20180427 |
WO-2017011776-A1 | Substituted pyrazolo[1,5-a]pyridine compounds as ret kinase inhibitors | 20150716 |
EP-3305794-A1 | Selective modulators of the activity of the gpr55 receptor: chromenopyrazole derivatives | 20150505 |
Complexity: | 190 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 184.121177757 |
Formal Charge: | 0 |
Heavy Atom Count: | 13 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 184.121177757 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 41.6 Å2 |
Undefined Atom Stereocenter Count: | 1 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | -0.5 |
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