1-Methyl-2-piperidinemethanol - CAS 20845-34-5
Catalog: |
BB016344 |
Product Name: |
1-Methyl-2-piperidinemethanol |
CAS: |
20845-34-5 |
Synonyms: |
(1-methylpiperidin-2-yl)methanol |
IUPAC Name: | (1-methylpiperidin-2-yl)methanol |
Description: | 1-Methyl-2-piperidinemethanol (CAS# 20845-34-5) is used as a reagent to synthesize phenylpyridone derivatives, compounds that act as anti-obesity agents in mice. |
Molecular Weight: | 129.20 |
Molecular Formula: | C7H15NO |
Canonical SMILES: | CN1CCCCC1CO |
InChI: | InChI=1S/C7H15NO/c1-8-5-3-2-4-7(8)6-9/h7,9H,2-6H2,1H3 |
InChI Key: | HXXJMMLIEYAFOZ-UHFFFAOYSA-N |
Boiling Point: | 79-80 °C (7 mmHg) |
Melting Point: | -20 °C |
Purity: | 98 % |
Density: | 0.984 g/cm3 |
Appearance: | Clear brown liquid |
Storage: | Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. |
MDL: | MFCD00006494 |
LogP: | 0.40090 |
GHS Hazard Statement: | H227 (16.67%): Combustible liquid [Warning Flammable liquids] |
Precautionary Statement: | P210, P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P370+P378, P403+P233, P403+P235, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
WO-2021198020-A1 | 3-(anilino)-2-[3-(3-alkoxy-pyridin-4-yl]-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one derivatives as egfr inhibitors for the treatment of cancer | 20200331 |
WO-2021152149-A1 | Ras inhibitors and methods of using the same | 20200131 |
WO-2020216774-A1 | 4h-pyrrolo[3,2-c]pyridin-4-one derivatives | 20190424 |
WO-2020117942-A1 | Choline metabolism inhibitors | 20181204 |
US-10689377-B2 | KRas G12C inhibitors | 20171115 |
PMID | Publication Date | Title | Journal |
21971827 | 20120301 | Comparison of polymeric siRNA nanocarriers in a murine LPS-activated macrophage cell line: gene silencing, toxicity and off-target gene expression | Pharmaceutical research |
21118719 | 20110401 | Gene silencing activity of siRNA polyplexes based on biodegradable polymers | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V |
Complexity: | 85 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 129.115364102 |
Formal Charge: | 0 |
Heavy Atom Count: | 9 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 129.115364102 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 23.5 Å2 |
Undefined Atom Stereocenter Count: | 1 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 0.5 |
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Alcohols and Derivatives
Piperidines
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