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1-Hydroxy-2,2,6,6-tetramethyl-4-hydroxypiperidinium Chloride

1-Hydroxy-2,2,6,6-tetramethyl-4-hydroxypiperidinium Chloride - CAS 4972-11-6

Catalog:	BB060827
Product Name:	1-Hydroxy-2,2,6,6-tetramethyl-4-hydroxypiperidinium Chloride
CAS:	4972-11-6
Synonyms:	1-Hydroxy-2,2,6,6-tetramethyl-4-piperidinol hydrochloride; 1,4-Dihydroxy-2,2,6,6-tetramethylpiperidin-1-ium chloride

Technical Data

Description:	2,2,6,6-Tetramethylpiperidine-1,4-diol is related to 4-Hydroxy-2,2,6,6-tetramethyl-1-piperidinyloxy (H956500), which is a free radical scavenger. 2,2,6,6-Tetramethylpiperidine-1,4-diol has also been shown to be an in vitro and in vivo radioprotector. It is used as a reagent in stereoselective preparation of tetrasubstituted triarylated olefins via Pd-catalyzed sequential oxidative Heck arylation of alkenes with arylboronic acids using nitroxides as oxidants.
Molecular Weight:	209.71
Molecular Formula:	C9H20ClNO2
Melting Point:	>208°C (dec.)
Solubility:	DMSO (Slightly), Methanol (Slightly)
Appearance:	White to Off-White Solid
Storage:	Hygroscopic, -20°C Freezer, Under inert atmosphere
References:	Flather, M., et al. Lancet, 355, 1575 (2000); Sasso, F., et al. Metabolism, 52, 675 (2003); Kass, D., et al. Circ. Res., 94, 1533 (2004); Murdoch, C., et al. Cardiovasc Res., 71, 208 (2006); Hahn, M., et al. Free Radic. Biol. Med., 28, 953 (2000); He, Z., et al. Angew. Chem. Int. Ed., 51, 3699 (2012).

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