((1-Chloro-2-methylpropan-2-yl)oxy)trimethylsilane - CAS 31557-15-0

Catalog: BB069173
Product Name: ((1-Chloro-2-methylpropan-2-yl)oxy)trimethylsilane
CAS: 31557-15-0
Description:((1-Chloro-2-methylpropan-2-yl)oxy)trimethylsilane is an intermediate for the synthesis of 3-Hydroxy Bortezomib (H818150), which is a metabolite of Bortezomib (B675700); the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer.
Molecular Weight:180.75
Molecular Formula:C7H17ClOSi
Solubility:Dichloromethane; Ethyl Ether
Appearance:Clear Colorless Oil
References:Nawrocki, S.T., et al. Cancer Res., 65, 11510 (2005); Drahl, C. Chem. and Eng. News, 87, 41 (2009).

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