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| Description: | ((1-Chloro-2-methylpropan-2-yl)oxy)trimethylsilane is an intermediate for the synthesis of 3-Hydroxy Bortezomib (H818150), which is a metabolite of Bortezomib (B675700); the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. |
| Molecular Weight: | 180.75 |
| Molecular Formula: | C7H17ClOSi |
| Solubility: | Dichloromethane; Ethyl Ether |
| Appearance: | Clear Colorless Oil |
| References: | Nawrocki, S.T., et al. Cancer Res., 65, 11510 (2005); Drahl, C. Chem. and Eng. News, 87, 41 (2009). |
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