1-Cbz-4-aminopiperidine - CAS 120278-07-1
Catalog: |
BB004772 |
Product Name: |
1-Cbz-4-aminopiperidine |
CAS: |
120278-07-1 |
Synonyms: |
4-amino-1-piperidinecarboxylic acid (phenylmethyl) ester; benzyl 4-aminopiperidine-1-carboxylate |
IUPAC Name: | benzyl 4-aminopiperidine-1-carboxylate |
Description: | 1-Cbz-4-aminopiperidine (CAS# 120278-07-1) is a chemical reagent used in the synthesis of fluoro-olefins as peptidomimetic inhibitors of dipeptidyl peptidases. Also used in the synthesis of β-lactamase inhibitors for treatment of bacterial infections which are resistant to β-lactam antibiotics. |
Molecular Weight: | 234.29 |
Molecular Formula: | C13H18N2O2 |
Canonical SMILES: | C1CN(CCC1N)C(=O)OCC2=CC=CC=C2 |
InChI: | InChI=1S/C13H18N2O2/c14-12-6-8-15(9-7-12)13(16)17-10-11-4-2-1-3-5-11/h1-5,12H,6-10,14H2 |
InChI Key: | YYIQGSYCCNQAGV-UHFFFAOYSA-N |
Boiling Point: | 367.2 ℃ at 760 mmHg |
Density: | 1.151 g/cm3 |
Storage: | Keep in dark place, Inert atmosphere, Room temperature |
MDL: | MFCD05863884 |
LogP: | 2.38450 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
WO-2021133915-A1 | Ectonucleotide pyrophosphatase/phosphodiesterase 1 (enpp1) modulators and uses thereof | 20191223 |
WO-2021083949-A1 | Bifunctional compounds for the treatment of cancer | 20191029 |
WO-2021067569-A1 | Substituted 1, 6-naphthyridine inhibitors of cdk5 | 20191001 |
WO-2020132561-A1 | Targeted protein degradation | 20181220 |
EP-3897631-A1 | Targeted protein degradation | 20181220 |
Complexity: | 244 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 234.136827821 |
Formal Charge: | 0 |
Heavy Atom Count: | 17 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 234.136827821 |
Rotatable Bond Count: | 3 |
Topological Polar Surface Area: | 55.6 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1.2 |
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