1-Boc-4-fluoro-4-(hydroxymethyl)piperidine - CAS 614730-97-1

Name: 1-Boc-4-fluoro-4-(hydroxymethyl)piperidine
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog:	BB031126
Product Name:	1-Boc-4-fluoro-4-(hydroxymethyl)piperidine
CAS:	614730-97-1
Synonyms:	4-fluoro-4-(hydroxymethyl)-1-piperidinecarboxylic acid tert-butyl ester; tert-butyl 4-fluoro-4-(hydroxymethyl)piperidine-1-carboxylate

Technical Data

IUPAC Name:	tert-butyl 4-fluoro-4-(hydroxymethyl)piperidine-1-carboxylate
Description:	1-Boc-4-fluoro-4-(hydroxymethyl)piperidine (CAS# 614730-97-1) is used in preparation of heterocyclic compounds as BCL 2 inhibitors.
Molecular Weight:	233.28
Molecular Formula:	C11H20FNO3
Canonical SMILES:	CC(C)(C)OC(=O)N1CCC(CC1)(CO)F
InChI:	InChI=1S/C11H20FNO3/c1-10(2,3)16-9(15)13-6-4-11(12,8-14)5-7-13/h14H,4-8H2,1-3H3
InChI Key:	BWZOULIMVKCGII-UHFFFAOYSA-N
Boiling Point:	311.017 °C at 760 mmHg
Density:	1.137 g/cm³
MDL:	MFCD08062513
LogP:	1.65580

Publication Number	Title	Priority Date
WO-2021207172-A1	Compounds and methods for targeted degradation of kras	20200406
WO-2021127337-A1	Trpml modulators	20191219
CN-112661751-A	Heterocyclic compounds as BCL-2 inhibitors	20191016
WO-2021066873-A1	Condensed heterocycles as bcl-2 inhibitors	20191003
WO-2021023271-A1	Crystal form of compound as prostacyclin receptor agonist and preparation method therefor	20190806

Complexity:	254
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	233.14272166
Formal Charge:	0
Heavy Atom Count:	16
Hydrogen Bond Acceptor Count:	4
Hydrogen Bond Donor Count:	1
Isotope Atom Count:	0
Monoisotopic Mass:	233.14272166
Rotatable Bond Count:	3
Topological Polar Surface Area:	49.8
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	1.1