1-Boc-4-aminopiperidine-4-carboxylic acid - CAS 183673-71-4
Catalog: |
BB014081 |
Product Name: |
1-Boc-4-aminopiperidine-4-carboxylic acid |
CAS: |
183673-71-4 |
Synonyms: |
L-Pip(Boc)-OH; 4-Amino-1-Boc-isonipecotic acid; 4-Amino-1-(tert-butoxycarbonyl)piperidine-4-carboxylic acid; 4-Amino-1-Boc-piperidine-4-carboxylic acid |
IUPAC Name: | 4-amino-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-4-carboxylic acid |
Description: | An a,a-Disubstituted amino acid for preparation of water-soluble highly helical peptides. |
Molecular Weight: | 244.29 |
Molecular Formula: | C11H20N2O4 |
Canonical SMILES: | CC(C)(C)OC(=O)N1CCC(CC1)(C(=O)O)N |
InChI: | InChI=1S/C11H20N2O4/c1-10(2,3)17-9(16)13-6-4-11(12,5-7-13)8(14)15/h4-7,12H2,1-3H3,(H,14,15) |
InChI Key: | YNHLVALLAURVJF-UHFFFAOYSA-N |
Boiling Point: | 380.1 °C at 760 mmHg |
Melting Point: | 289-294 °C |
Purity: | ≥ 98 % (HPLC) |
Density: | 1.203 g/cm3 |
Appearance: | White solid |
Storage: | Store at 2-8 °C |
MDL: | MFCD01318728 |
LogP: | 1.43760 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] |
Precautionary Statement: | P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
WO-2021078132-A1 | Inhibitors of mtor-mediated induction of autophagy | 20191021 |
US-2021094933-A1 | Rapafucin derivative compounds and methods of use thereof | 20191001 |
WO-2021067439-A1 | Rapafucin derivative compounds and methods of use thereof | 20191001 |
WO-2020114474-A1 | Heterocyclic compound, application thereof and pharmaceutical composition containing same | 20181206 |
WO-2019215341-A1 | Furin inhibitors | 20180511 |
Complexity: | 314 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 244.14230712 |
Formal Charge: | 0 |
Heavy Atom Count: | 17 |
Hydrogen Bond Acceptor Count: | 5 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 244.14230712 |
Rotatable Bond Count: | 3 |
Topological Polar Surface Area: | 92.9 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | -2.2 |
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