1-Boc-3-amino-4-hydroxypiperidine - CAS 454709-92-3
Catalog: |
BB025881 |
Product Name: |
1-Boc-3-amino-4-hydroxypiperidine |
CAS: |
454709-92-3 |
Synonyms: |
3-amino-4-hydroxy-1-piperidinecarboxylic acid tert-butyl ester; tert-butyl 3-amino-4-hydroxypiperidine-1-carboxylate |
IUPAC Name: | tert-butyl 3-amino-4-hydroxypiperidine-1-carboxylate |
Description: | 1-Boc-3-amino-4-hydroxypiperidine (CAS# 454709-92-3) is a reactant that has been used in the preparation of β-aminoacylpiperidines as dipeptidyl peptidase IV inhibitors. |
Molecular Weight: | 216.28 |
Molecular Formula: | C10H20N2O3 |
Canonical SMILES: | CC(C)(C)OC(=O)N1CCC(C(C1)N)O |
InChI: | InChI=1S/C10H20N2O3/c1-10(2,3)15-9(14)12-5-4-8(13)7(11)6-12/h7-8,13H,4-6,11H2,1-3H3 |
InChI Key: | LUQURLQDYAJECW-UHFFFAOYSA-N |
Appearance: | Powder |
LogP: | 0.95360 |
GHS Hazard Statement: | H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
WO-2021171163-A1 | Combinations of diacylglycerol acyltransferase 2 inhibitors and acetyl-coa carboxylase inhibitor | 20200224 |
CA-3095028-A1 | Diacylglycerol acyltransferase 2 inhibitor | 20191004 |
US-2021100796-A1 | Diacylglycerol acyl transferase 2 inhibitor | 20191004 |
US-2021100798-A1 | Diacylglycerol acyl transferase 2 inhibitor | 20191004 |
US-11065249-B2 | Diacylglycerol acyl transferase 2 inhibitor | 20191004 |
Complexity: | 237 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 216.14739250 |
Formal Charge: | 0 |
Heavy Atom Count: | 15 |
Hydrogen Bond Acceptor Count: | 4 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 216.14739250 |
Rotatable Bond Count: | 2 |
Topological Polar Surface Area: | 75.8 Å2 |
Undefined Atom Stereocenter Count: | 2 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | -0.2 |
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