[1,6]Naphthyridine - CAS 253-72-5

Catalog:	BB018886
Product Name:	[1,6]Naphthyridine
CAS:	253-72-5
Synonyms:	1,6-naphthyridine

Technical Data

Safety and Hazards

Patents

Literatures

Computed Properties

IUPAC Name:	1,6-naphthyridine
Description:	[1,6]Naphthyridine (CAS# 253-72-5 ) is a useful research chemical.
Molecular Weight:	130.15
Molecular Formula:	C8H6N2
Canonical SMILES:	C1=CC2=C(C=CN=C2)N=C1
InChI:	InChI=1S/C8H6N2/c1-2-7-6-9-5-3-8(7)10-4-1/h1-6H
InChI Key:	VSOSXKMEQPYESP-UHFFFAOYSA-N
Boiling Point:	267.3 °C at 760 mmHg
Melting Point:	231-233 °C
Purity:	98 %
Density:	1.183 g/cm³
MDL:	MFCD00059750
LogP:	1.62980

Publication Number	Title	Priority Date
WO-2021126995-A1	Methods and compositions for treating cancer	20191220
WO-2021127265-A1	Compounds and probes for imaging huntingtin protein	20191218
WO-2021122745-A1	4-[[(7-aminopyrazolo[1,5-a]pyrimidin-5-yl)amino]methyl]piperidin-3-ol compounds and their therapeutic use	20191216
US-2021188827-A1	Atm kinase inhibitors and compositions and methods of use thereof	20191204
WO-2021113506-A1	Atm kinase inhibitors and compositions and methods of use thereof	20191204

PMID	Publication Date	Title	Journal
27326329	20160609	2,8-Disubstituted-1,6-Naphthyridines and 4,6-Disubstituted-Isoquinolines with Potent, Selective Affinity for CDK8/19	ACS medicinal chemistry letters
22900966	20121022	Exploring the role of water molecules for docking and receptor guided 3D-QSAR analysis of naphthyridine derivatives as spleen tyrosine kinase (Syk) inhibitors	Journal of chemical information and modeling
22472093	20120420	Suberitine A-D, four new cytotoxic dimeric aaptamine alkaloids from the marine sponge Aaptos suberitoides	Organic letters
22321214	20120301	Discovery of 4-hydroxy-1,6-naphthyridine-3-carbonitrile derivatives as novel PDE10A inhibitors	Bioorganic & medicinal chemistry letters
22356552	20120301	Evaluation of WO2011134971, chiral 1,6-napthyridine Syk kinase inhibitors	Expert opinion on therapeutic patents

Related Products

Online Inquiry

Name:

* Phone:

* Service & Products of Interested:

Project Description:

* Quantity:

* Email:

* Verification Code:

Customer Support

If the product you need is not in our catalog, please contact us in time to submit your needs. You can help our website get better and better. Why not submit the request today?

Submit Requirement

Customer Centered

Global Delivery

Warehouses in multiple cities to ensure fast delivery

Quality Assurance

Strict process parameter control to ensure product quality

Large Stock

> 20,000 building blocks and intermediates from stock

Process Scale-up

Process scale-up from lab to industrial scale

Flexible Batch Size

Flexible batch size for diverse industrial demands

Related Functional Groups

Naphthyridines

[40499-89-6]
2,7-naphthyridine-4-carboxylic acid
[959617-73-3]
Tert-butyl 1,5-naphthyridin-3-ylcarbamate
[1303588-27-3]
7-Chloro-1,2,3,4-tetrahydro-1,8-naphthyridine
[952059-69-7]
8-Chloro-3-methoxy-[1,5]naphthyridine
[1203499-56-2]
2-(Dimethoxymethyl)-6-methyl-1,8-naphthyridine
[2708278-69-5]
Ethyl 2-aminohex-5-enoate hydrochloride

Customers Also Viewed

[332360-02-8]
Mitoguazone dihydrochloride monohydrate
[1866059-82-6]
1,1,2,2-Tetrafluoro-3-methylsulfonylpropane
[852913-16-7]
N-[3,5-Bis(trifluoromethyl)phenyl]-N-[(8a,9S)-6-methoxy-9-cinchonanyl]thiourea
[10128-55-9]
N-[2-(4-oxo-4H-3,1-benzoxazin-2-yl)phenyl]-2-naphthalenesulfonamide
[433335-00-3]
N-Boc-(tosyl)methylamine
[883-44-3]
N-(3-Hydroxypropyl)phthalimide

INDUSTRY LEADERS TRUST OUR PRODUCTS

Phone

US & Canada (Toll free):

UK:

International:

E-mail & Fax

E-mail:

Fax:

Address

USA:

UK:

Our Products

Inquiry Basket

Loading ......

Delete selected Go to checkout

GHS Hazard Statement:	H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]
Precautionary Statement:	P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word:	Warning

Complexity:	114
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	130.053098200
Formal Charge:	0
Heavy Atom Count:	10
Hydrogen Bond Acceptor Count:	2
Hydrogen Bond Donor Count:	0
Isotope Atom Count:	0
Monoisotopic Mass:	130.053098200
Rotatable Bond Count:	0
Topological Polar Surface Area:	25.8 Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	1.1