1-(4-Bromophenyl)piperazine Hydrochloride - CAS 68104-62-1
Catalog: |
BB033471 |
Product Name: |
1-(4-Bromophenyl)piperazine Hydrochloride |
CAS: |
68104-62-1 |
Synonyms: |
1-(4-bromophenyl)piperazine;hydrochloride; 1-(4-bromophenyl)piperazine;hydrochloride |
IUPAC Name: | 1-(4-bromophenyl)piperazine;hydrochloride |
Description: | 1-(4-Bromophenyl)piperazine Hydrochloride (CAS# 68104-62-1) is useful in the synthesis of large bifunctional heterocycles use in targeted degradation of rapidly accelerated fibrosarcoma polypeptides. |
Molecular Weight: | 277.59 |
Molecular Formula: | C10H14BrClN2 |
Canonical SMILES: | C1CN(CCN1)C2=CC=C(C=C2)Br.Cl |
InChI: | InChI=1S/C10H13BrN2.ClH/c11-9-1-3-10(4-2-9)13-7-5-12-6-8-13;/h1-4,12H,5-8H2;1H |
InChI Key: | YDVSFRZKQMQPJD-UHFFFAOYSA-N |
Boiling Point: | 353.3 °C at 760 mmHg |
Solubility: | Water : Soluble |
Appearance: | White to off-white powder or crystals |
MDL: | MFCD00674134 |
LogP: | 3.05450 |
GHS Hazard Statement: | H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
WO-2020227325-A1 | Heterobifunctional compounds as degraders of hpk1 | 20190506 |
EP-3556761-A1 | Pyrrolo-aromatic heterocyclic compound, preparation method therefor, and medical use thereof | 20170208 |
US-2020062749-A1 | Pyrrolo-aromatic heterocyclic compound, preparation method therefor, and medical use thereof | 20170208 |
EP-3556761-B1 | Pyrrolo-aromatic heterocyclic compound, preparation method therefor, and medical use thereof | 20170208 |
US-2018179183-A1 | Compounds and methods for the targeted degradation of rapidly accelerated fibrosarcoma polypeptides | 20161223 |
Complexity: | 149 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 2 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 276.00289 |
Formal Charge: | 0 |
Heavy Atom Count: | 14 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 276.00289 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 15.3 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
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